Results 41 to 50 of about 12,236,846 (252)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Vatandaş Sözleşmeleri: Farklı Ülkelerdeki Uygulamalar ve Genel Değerlendirme

Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2010
VatandaşSözleşmeleri kamu kurumlarının hizmet standartları, bilgi, şikayet, nezaket, seçim ve danışma, erişebilirlik, ayırım yapmama, kamu parasına değer verme bağlamında vatandaşlara/müşterilere yönelik sistematik çabalarınıtemsil eden belgelerdir ...
Selim Coşkun
doaj  

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

PUBLIC INVESTMENT CHALLENGES AND REFORMS IN ROMANIA [PDF]

Buletin ştiinţific: Universitatea din Piteşti. Seria Ştiinţe Economice, 2019
The public investments play an important role in stimulating the economic growth and in reducing the disparities between urban and rural areas or between the regions of a country.
Daniela PIRVU, Claudia STANCIU-TOLEA
doaj  

Public Health Law Reform

American Journal of Public Health, 2001
Public health law reform is necessary because existing statutes are outdated, contain multiple layers of regulation, and are inconsistent. A model law would define the mission and functions of public health agencies, provide a full range of flexible powers, specify clear criteria and procedures for activities, and provide protections for privacy and ...
openaire   +3 more sources

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

Epigenetic Silencing of CYYR1 Promotes Lung Adenocarcinoma Progression Through TRIM21‐Dependent Regulation of HMMR Stability

Advanced Science, EarlyView.
CYYR1 as an epigenetically dysregulated tumor‐suppressive factor that influences oncoprotein stability through TRIM21‐dependent HMMR regulation and reveals a potential therapeutic vulnerability in CYYR1‐deficient LUAD. The graphical illustration was created using FigDraw (www.figdraw.com).
Fengsheng Dai, Jingyi Tang, Huan Rong, Yu Wang, Xiangyi Zhou, Can Xu, Jianhua Wang, Lili Li, Yue Wu, Fei Deng, Dan Yang, Xiao Yang, Renyan Li, Yongzhong Wu, Dongxi Xiang, Tingxiu Xiang   +15 more
wiley   +1 more source

In Situ CO2‐Induced Hydrogels for Enhancing Carbon Sequestration in Saline Aquifers

Advanced Science, EarlyView.
A novel integrated method that combines in situ CO2‐induced phase‐transition hydrogels formed by a C22‐tailed tertiary amine dispersion with tailored deep eutectic solvents to increase CO2 sequestration in saline aquifers. ABSTRACT Carbon sequestration in saline aquifers underpins global net‑zero emission goals, yet existing CO2 storage capacity ...
Fuchuan Liu, Xinjie Luo, Dianguo Wu, Xuezhi Zhao, Yan Zhang, Yujun Feng   +5 more
wiley   +1 more source

Public procurement trajectories in Tanzania: a review of reforms, practices, and compliance

Cogent Business & Management
Over decades, public procurement in Tanzania experienced critical reforms; however, not much is known about the reforms and hence there is a dearth of comprehensive reviews about them.
Alban D. Mchopa, Ismail Abdi Changalima, Gabriel R. Sulle, Rahim M. Msofe   +3 more
doaj   +1 more source

Public Administration Reform

Academic and Applied Research in Military and Public, 2022
The Republic of Kazakhstan is one of the countries of Central Asia which is actively working to improve the apparatus of public administration. The formation of the Republic of Kazakhstan as a sovereign state, the ongoing socio-economic reforms in the country and market relations have necessitated a transition to a new administrative mechanism.
openaire   +2 more sources