Sexual abuse and substance use before or during sex among transgender women in Brazil. [PDF]
Martins RS +9 more
europepmc +1 more source
ABSTRACT High levels of parental stress and psychological inflexibility are common among caregivers raising children with neurodevelopmental disabilities. Navigator ACT is a group‐based treatment developed to increase psychological flexibility and reduce the impact of stress among parents of children with various disabilities (e.g., autism spectrum ...
T. Holmberg Bergman +3 more
wiley +1 more source
Environmental exposures, microbiome dynamics and chronic disease risk in climate-vulnerable regions: interdisciplinary perspectives from Puerto Rico. [PDF]
Godoy-Vitorino F +10 more
europepmc +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Mapping the landscape of managed entry agreements: a systematic review of global frameworks, system-level components, and implementation challenges. [PDF]
Al-Omar HA +17 more
europepmc +1 more source
Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen +4 more
wiley +1 more source
Prevalence of the double burden of malnutrition and its association with ideal cardiovascular health in Brazilian children. [PDF]
Viana RS +2 more
europepmc +1 more source
Aims This work aimed to correlate potential links between the suspected adverse drug reaction (ADR) profile of licensed nonsteroidal androgen receptor antagonists (NSARA) with their unique chemical properties and known off‐target polypharmacology. Methods Physicochemical and polypharmacology data were curated from the Electronic Medicines Compendium ...
Simrit Dhillon +2 more
wiley +1 more source
Patient and Public Involvement (PPI) in lab-based research. What is the added value? Reflections from a researcher and public contributor perspective. [PDF]
Hatch S, Formosa N.
europepmc +1 more source
A scoping review of quality prescribing indicators, rules and criteria for primary care
Medication‐related problems (MRPs) place a substantial burden on the healthcare system, contributing to hospital admissions and significant healthcare costs. Quality prescribing indicators (QPIs), rules and criteria serve to educate prescribers about high risk MRPs and to monitor prescribing behaviours. This study aims to summarize existing indicators,
James Nind +6 more
wiley +1 more source

