Results 41 to 50 of about 3,337,668 (303)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Increasing Safety in America's Public Schools [PDF]

open access: yes, 2001
As the Public Education Network (PEN) and its member local education funds (LEFs) are committed to creating systems of public education that result in high achievement for every child, we believe that equal opportunity, access to quality public schools ...
Beth Bacon
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Study on Exterior Wall Tile Degradation Conditions of High-rise Buildings in Taoyuan City

open access: yesJournal of Asian Architecture and Building Engineering, 2018
In recent years in Taiwan, pedestrians have been injured by external wall tiles falling from high-rise buildings. In numerous cases, exposure to temperature and/or seismic behavior caused the tiles to fall off.
Chu-Tsen Liao
doaj   +1 more source

Substance Abuse Treatment and Public Safety [PDF]

open access: yes, 2008
The Substance Abuse Treatment and Public Safety brief found that the sooner substance abuse is treated, the bigger the long-term cost savings and increases in public safety.

core  

Public safety and cognitive radio [PDF]

open access: yes, 2009
This book gives comprehensive and balanced coverage of the principles of cognitive radio communications, cognitive networks, and details of their implementation, including the latest developments in the standards and spectrum policy. Case studies, end-of-
Heskamp, Marnix   +2 more
core   +3 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Deprivation of Liberty: Has the European Court of Human Rights Recognised a ‘Public Safety’ Exception?

open access: yesMerkourios, 2013
The European Court of Human Rights held in Austin & Others v The United Kingdom that the police confinement of a crowd of protestors for up to seven hours, or 'kettling', did not constitute a deprivation of liberty in violation of Article 5 of the ...
Donna Cline
doaj   +3 more sources

Silencers: A Threat to Public Safety [PDF]

open access: yes, 2017
A push by the firearms industry and gun lobby to make it far easier for private citizens to buy and possess firearm silencers will only place the police and public at increased risk warns a new and expanded edition of the Violence Policy Center's (VPC ...

core  

The Obamacare Opportunity: Implementing the Affordable Care Act to Improve Health, Reduce Hardship, and Grow the Economy for All Californians [PDF]

open access: yes, 2013
This report describes how California can take advantage of ACA implementation to increase access both to health coverage and to vital safety net and work support programs.In Section I, we describe California's public benefit take up problem.
Katherine Adamides   +2 more
core   +1 more source

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