Results 131 to 140 of about 1,356,450 (345)

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

open access: yesAdvanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou   +9 more
wiley   +1 more source

The Evolution of Normative Legal Scholarship: The Case of Copyright Discourse [PDF]

open access: yes, 2012
Legal scholarship’s central function is to provide normative advice about the law. However, some academics have challenged the imp ortance of such scholarship.
Goold, P.
core   +1 more source

PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping

open access: yesAdvanced Science, EarlyView.
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su   +7 more
wiley   +1 more source

Room‐Temperature Antiferroelectricity in Titanite (CaTiSiO5) Thin Films

open access: yesAdvanced Electronic Materials, EarlyView.
This study reports the first fabrication of titanite films featuring 1D chains of oxygen octahedra, along with the first observation of their antiferroelectric behavior at room temperature. A field‐induced ferroelectric phase is observed at ∼430 kV/cm, which is not reported in bulk titanite.
Weirong Yang   +3 more
wiley   +1 more source

Amy Werbel

open access: yesPanorama, 2019
Amy Werbel
doaj   +1 more source

Assessing Atlanta’s Placed-Based College Scholarship

open access: yesAERA Open
We investigate whether and how Achieve Atlanta’s college scholarship and associated services impact college enrollment, persistence, and graduation among Atlanta Public School graduates experiencing low household income. Qualifying for the scholarship of
Carycruz Bueno   +2 more
doaj   +1 more source

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