Results 81 to 90 of about 13,711,001 (247)

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Macrophage Trogocytosis of Tumor Cells Drives the Immunosuppression of Tumor Microenvironment

Advanced Science, EarlyView.
Trogocytosis efficiency varies significantly among different tumor cells and is inversely related to their cortical stiffness; this efficiency dictates the extent of immunosuppression via upregulation of CXCL5 and Arg‐1, ultimately driving CD8+T cell exhaustion and tumor escape.
Chao Liang, Jiaqi He, Wan‐Ru Zhuang, Yao Lei, Yanru Jiang, Xianbin Ma, Pan Liu, Zhujun Jiang, Yongheng Li, Hai‐Yan Xie   +9 more
wiley   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

22nd Annual Chicano Scholarship Awards 1997; The Chicano Scholarship Fund Committee and KUED-TV present: Twenty-second Annual Chicano Scholarship Awards

, 1997
Video of interviews with the 1997 Scholarship recipients, students and professionals of Chicano or Latino backgrounds, talking about their background experiences, educational goals, and professional aspirations.
University of Utah. Chicano Scholarship Fund Committee
core  

Defining and supporting the Scholarship of Teaching and Learning (SoTL): a sector-wide study. (Executive summary) [PDF]

, 2016
This project was carried out in the context of the HEA ‘Staff Transitions’ stream of work, with a view to investigating the extent to which activities undertaken under the banner of the Scholarship of Teaching and Learning (SoTL) might inform a sector ...
Fanghanel, Joelle, Pritchard, Jane, Potter, Jacqueline, Wisker, Gina   +3 more
core   +1 more source

Toward Open Public Administration Scholarship

, 2010
This essay focuses on the potential of information communication technologies to move the Public Administration (PA) scholarly community into a new information paradigm.
Z. J. Zhao, Sandfort, Jodi, Mergel, Ines, Sandfort, Jodi R., C. M. Schweik, I. Mergel, J. R. Sandfort, Schweik, Charles M, Schweik, Charles M., Zhao, Zhirong J., Zhao, Zhirong   +10 more
core   +1 more source

Longitudinal Multifrequency MR Elastography Reveals Biomechanical Signatures of Progression in a Translational Liver Tumor Model

Advanced Science, EarlyView.
Longitudinal multifrequency magnetic resonance elastography (mMRE) performed on a clinical 3 Tesla magnetic resonance imaging system reveals early biomechanical alterations during liver tumor progression in a translational VX2 model. Changes in tumor stiffness and viscosity precede diffusion‐related alterations and are associated with extracellular ...
Justus Ramtke, Friederike Hesse, Lasse Noack, Justus Klockner, Yubei He, Yu Liu, Yanglei Wu, Robin Schmidt, Selma Saclier, Salma A. S. Abosabie, Tom Meyer, Richard Ruppel, Nikolaus Berndt, Michael Mülleder, Eyk Schellenberger, Nicola Beindorff, Dominik N. Müller, Ingolf Sack, Jing Guo, Shraga Nahum Goldberg, Lynn Jeanette Savic   +20 more
wiley   +1 more source

37th Annual Chicano Scholarship Awards 2012

, 2012
Video of interviews with the 2011 Scholarship recipients, students and professionals of Chicano or Latino backgrounds, talking about their background experiences, educational goals, and professional aspirations.
University of Utah. Chicano Scholarship Fund Committee
core  

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

21st Annual Chicano Scholarship Awards 1996; The Chicano Scholarship Fund Committee and KUED-TV present: Twenty-first Annual Chicano Scholarship Awards

, 1996
Video of interviews with the 1996 Scholarship recipients, students and professionals of Chicano or Latino backgrounds, talking about their background experiences, educational goals, and professional aspirations.
University of Utah. Chicano Scholarship Fund Committee
core