Results 41 to 50 of about 2,955,878 (304)
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
On formal verification of arithmetic-based cryptographic primitives
Cryptographic primitives are fundamental for information security: they are used as basic components for cryptographic protocols or public-key cryptosystems.
A.C. Yao +11 more
core +1 more source
Agri-Food Traceability Management using a RFID System with Privacy Protection [PDF]
In this paper an agri-food traceability system based on public key cryptography and Radio Frequency Identification (RFID) technology is proposed. In order to guarantee safety in food, an efficient tracking and tracing system is required.
Bernardi, Paolo +5 more
core +2 more sources
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Demanding Quality Public Education In Tough Economic Times: What Voters Want from Elected Leaders [PDF]
Four years ago, Public Education Network launched an annual public opinion survey that focuses on defining what Americans value about public education and what voters want their elected leaders to do to raise achievement for all children.
core
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
A Neural Relation Extraction Model for Distant Supervision in Counter-Terrorism Scenario
Natural language processing (NLP) is the best solution to extensive, unstructured, complex, and diverse network big data for counter-terrorism. Through the text analysis, it is the basis and the most critical step to quickly extract the relationship ...
Jiaqi Hou +5 more
doaj +1 more source
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Criminal Trajectory Reconstruction Method Based on a Mobile Reference System
Criminal trajectory reconstruction is a crucial area of study in the investigative and evidentiary processes of public security departments. This paper proposes a method for reconstructing criminal trajectories based on a mobile reference system ...
Zhengyan Ding +4 more
doaj +1 more source

