Results 121 to 130 of about 1,015,564 (337)

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

The Relationship between Spiritual Intelligence and Emotional Intelligence with Self-Compassion of Nursing Students [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2019
Introduction: Self-compassion among nurses leads to spiritual care of the patients, which is an effective psychological component in the spiritual and emotional intelligence of nurses. The purpose of this study was to investigate the relationship between
Anahita Khodabakhshi Koolaee, Nazgol Chaeichi Tehrani, Akram Sanagoo   +2 more
doaj  

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

Advanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang, Yuli Zhang, Zixin Kang, Jiayun Xiong, Ronghua Yang, Kang Ning   +5 more
wiley   +1 more source

Self-awareness in consumer behavior: validation of an abbreviated scale [PDF]

, 2017
La autoconciencia del individuo se refiere al hábito, tendencia o disposición a centrar su atención hacia dentro o fuera de uno mismo. Este constructo está compuesto por tres dimensiones: autoconciencia privada, autoconciencia pública y ansiedad social ...
López-Bonilla, Jesús Manuel, López-Bonilla, Luis Miguel   +1 more
core  

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Linearizing and Forecasting: A Reservoir Computing Route to Digital Twins of the Brain

Advanced Science, EarlyView.
A new approach uses simple neural networks to create digital twins of brain activity, capturing how different patterns unfold over time. The method generates and recovers key dynamics even from noisy data. When applied to fMRI, it predicts brain signals and reveals distinctive activity patterns across regions and individuals, opening possibilities for ...
Gabriele Di Antonio, Tommaso Gili, Andrea Gabrielli, Maurizio Mattia   +3 more
wiley   +1 more source

Relation between Self-Focused Attention and Sensitivity to Distortions of Own Face

Экспериментальная психология
90 volunteers (62 women), aged from 18 to 38 years participated in an experimental task of own face recognition in morphed images. The aim of the study was to examine the test-retest reliability of self-face recognition test scores, the ...
A.V. Bocharov, A.N. Savostyanov, P.D. Rudych, A.E. Saprygin, S.S. Tamozhnikov, G.G. Knyazyev   +5 more
doaj   +1 more source

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

Advanced Science, EarlyView.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su, Meng Yang, Xinfeng Wang, Pa Wu, Zongzhao Zhai   +4 more
wiley   +1 more source

Гравированный автопортрет и портрет гравера. К вопросу о самосознании и социальном статусе граверов в России второй половины XVIII века

Вивліоѳика
This paper examines the unique self-portrait prints which provide rich material for raising a number of previously overlooked questions related to Russian art in the age of Catherine the Great.
Залина Тетермазова
doaj   +1 more source

cuteHap: Haplotype‐Aware Structural Variant Detection in Phased Long‐Read Sequencing Data

Advanced Science, EarlyView.
cuteHap is a haplotype‐aware structural variant detection method designed for phased long‐read sequencing. By employing self‐adaptive clustering and credibility‐prioritized beam search algorithms, cuteHap generates accurate haplotype‐resolved calls and outperforms state‐of‐the‐art tools.
Shuqi Cao, Yadong Liu, Miao Cui, Runtian Gao, Weimin Guo, Guohua Wang, Yadong Wang, Tao Jiang   +7 more
wiley   +1 more source