Results 41 to 50 of about 18,688,598 (253)

A machine learning-based short-term forecasting method for heavy fog in Anhui Province of China

open access: yesScientific Reports
Based on hourly observations from expressway meteorological stations across Anhui Province and the fifth-generation atmospheric reanalysis (ERA5) data from the European Centre for Medium-Range Weather Forecasts (ECMWF) spanning from January 2011 to ...
Yan Sun   +5 more
doaj   +1 more source

Uncovering Inequities: The Role of Social Determinants of Health in Hospitalized Adolescents and Young Adults With Heavy Menstrual Bleeding

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres   +6 more
wiley   +1 more source

Circular on Guidelines on the Public Service Commission (State Corporations and Public Universities) Disciplinary Appeal Procedures 2024 [PDF]

open access: yes
The Public Service Commission has, pursuant to provisions of sections 74 and 75 of the PSC Act of 2017 and regulation 68 of the PSC Regulations 2020, developed the guidelines on the PSC (State Corporations and Public Universities) Disciplinary Appeal ...
The Public Service Commission
core   +1 more source

Public Service Media| Introduction ~ Public Service Media and Exposure Diversity

open access: yesInternational Journal of Communication, 2015
Exposure diversity is a relatively new and as yet to be explicitly formulated objective of contemporary media policy. While it holds certain potential—in particular in the messy digital space characterized by abundance and exponentially increased user ...
Natali Helberger, Mira Burri
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Public Service Media| Contemplating a “Public Service Navigator”: In Search of New- (and Better-) Functioning Public Service Media

open access: yesInternational Journal of Communication, 2015
The article is set against the backdrop of the reform of public-service broadcasting (PSB) institutions and results from the wide spread of digital technologies.
Mira Burri
doaj  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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