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Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Recent studies in academic writing have used coaching to develop specific skills and affective variables. There are limited studies on coaching academic writing using genre pedagogy (GP) with adult learners, specifically Indonesian EFL teachers.
Aunurrahman Aunurrahman +3 more
doaj +1 more source
The Changing Discourse of the Supreme Court [PDF]
[Excerpt] “Academics, judges, and other commentators complain that, for the past few decades, the Justices on the Supreme Court have been increasingly writing opinions that are unreadable for most American citizens.
Johnson, Stephen M.
core +1 more source
Sport, physical activity and the establishment of Health and Wellbeing Boards in Nottingham and Nottinghamshire [PDF]
This paper will examine the emergence of Health and Wellbeing Boards in Nottinghamshire and the City of Nottingham and explore the implications for sport and physical activity. At the time of writing the transfer of responsibilities for Public Health and
Acheson D. +14 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Number our days: A reflection on Psalm 90, a Moses Psalm
Lois Joy Armstrong
doaj +1 more source
Samuel Pepys and his experiences of music at Restoration theatres [PDF]
Restoration London was replete with opportunities to listen to music, even before the first public concerts were established. The Restoration theatre was one of the venues where Londoners had ample opportunity to listen to the newest compositions ...
Wiesecke, J.
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
We Don’t Want to Talk About It: Communication Strategies for Teaching Less Popular Subjects [PDF]
Some subjects are the unloved: the required course in academic writing, the required course in public speaking, the course in communication theory, the course in basic mathematics.
Geyer, Christine A +3 more
core +1 more source

