Results 101 to 110 of about 3,779,538 (300)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Writing across curriculum: Evaluating a faculty-centered approach [PDF]

open access: yes, 2006
This paper discusses research on a pilot study for implementing a Writing Across the Curriculum (WAC) program in the College of Business (CoB) at a California Public University.
Easter, Marilyn K   +1 more
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

"The Private Is Becoming Political"—Interdisciplinary Perspectives on Autobiographical Writing in the Horizon of the Culture of Remembering and Contemporary History

open access: yesForum: Qualitative Social Research, 2011
This essay focuses on autobiographical life-writing as a part of commemorative culture, i.e. in East and West Germany. It looks at the literary genre from a sociological point of view.
Carsten Heinze
doaj  

​Exploring Reticence to Write in L2

open access: yesCuadernos de Investigación Educativa
Developing writing proficiency is essential to communicative competence in foreign language learning, yet Uruguayan public secondary students frequently display reluctance toward writing in English, as noted by their teachers.
Gabriel Díaz Maggioli
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

City of Buffalo 2009-2010 Action Plan [PDF]

open access: yes, 2009
I am writing on behalf of the Partnership for the Public Good (PPG) to comment on the City of Buffalo’s 09-10 Action Plan. PPG’s mission is to help build a more just, sustainable, and culturally vibrant community through action-oriented research, policy ...
Magavern, Sam
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

“Getting Started”: A Pilot Introductory Narrative Writing Session for Interprofessional Faculty in Academic Health Sciences

open access: yesAdvances in Medical Education and Practice, 2022
Christy D Remein,1 Ellen Childs,2 Jennifer Beard,3 Lindsay B Demers,1 Emelia J Benjamin,1,4 Sarah L Wingerter5 1Department of Medicine, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA; 2Department of Health Law, Policy, and ...
Remein CD   +5 more
doaj  

Authorship as cultural performance: new perspectives in authorship studies [PDF]

open access: yes, 2012
This article proposes a performative model of authorship, based on the historical alternation between predominantly 'weak' and 'strong' author concepts and related practices of writing, publication and reading.
Berensmeyer, Ingo   +2 more
core   +1 more source

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