Results 71 to 80 of about 4,270,489 (300)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Increasing Time for Preparing a Candidate’s Dissertation and ‘Ageing’ of Young Scientists

open access: yesВысшее образование в России
Many researchers note the existence of systemic problems in the training of highly qualified scientific personnel, in particular candidates of science.
S. I. Pakhomov   +2 more
doaj   +1 more source

Dynamically generated cyclic dominance in spatial prisoner's dilemma games

open access: yes, 2010
We have studied the impact of time-dependent learning capacities of players in the framework of spatial prisoner's dilemma game. In our model, this capacity of players may decrease or increase in time after strategy adoption according to a step-like ...
Attila Szolnoki   +5 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

“An Assistant in Your Pocket”: How Generative AI Shapes the Publishing Practices of Russian Postgraduate Students

open access: yesВысшее образование в России
Generative artificial intelligence (GenAI) is a serious challenge for science and education. To investigate the key dimensions of its perception, we conducted an applied sociological study involving Russian postgraduate students.
E. A. Koval   +3 more
doaj   +1 more source

Analyzing the Development of Scientific Research in the Field of Digital Transformations [PDF]

open access: yesProblemi Ekonomiki
The article is devoted to determining the state and tendencies in the development of scientific research in the field of digital transformations using the tools of bibliometric analysis.
Bondarenko Dmytro V.   +2 more
doaj   +1 more source

Control of bone remodelling by applied dynamic loads [PDF]

open access: yes
The data showing the relationship between bone mass and peak strain magnitude prepared and submitted for publication. The data from experiments relating remodelling activity with static or dynamic loads were prepared and submitted for publication ...
Lanyon, L. E., Rubin, C. T.
core   +2 more sources

Identification of strong photometric activity in the components of LHS 1070 [PDF]

open access: yes, 2010
Activity in low-mass stars is an important ingredient in the evolution of such objects. Fundamental physical properties such as age, rotation, magnetic field are correlated with activity.
Aschwanden   +26 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Publication catalysis—lowering activation energy [PDF]

open access: yesThe EMBO Journal, 2018
Life Science Alliance is a new platform for and by the research community to increase the efficacy of publishing high‐quality research findings.
openaire   +2 more sources

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