Results 51 to 60 of about 819,739 (287)

Negative results provide valuable evidence for conservation

open access: yesPerspectives in Ecology and Conservation, 2020
A pervasive publication bias, whereby studies that report positive results are prioritised over those that report negative findings, has been shown to exist in the disciplines that conservation practice and policy draw information from. The bias reflects
Kevin A. Wood
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Publication bias and the canonization of false facts

open access: yeseLife, 2016
Science is facing a “replication crisis” in which many experimental findings cannot be replicated and are likely to be false. Does this imply that many scientific facts are false as well? To find out, we explore the process by which a claim becomes fact.
Silas Boye Nissen   +3 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Publication bias in laboratory animal research by non-publication of “negative” results

open access: yesAll Results Journals: Biol, 2013
An interesting publication for the readership of The All Results Journal appeared recently, focused on publication bias in laboratory animal research.
Cornelis J.F Van Noorden
doaj   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The Need for Formal Evidence Synthesis in Food Policy: A Case Study of Willingness-to-Pay

open access: yesAnimals, 2017
Meta-analysis is increasingly utilised in the understanding of consumer behaviour, including in relation to farm animal welfare. However, the issue of publication bias has received little attention.
Beth Clark   +3 more
doaj   +1 more source

Effect of Publication Bias on Retrieval Bias

open access: yesAcademic Medicine, 2002
Publication bias is the main etiologic factor in retrieval bias. The authors measured the influence a positive study outcome had on housestaff's selecting the study for presentation.
Craig E, Daniels   +2 more
openaire   +3 more sources

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