Results 121 to 130 of about 1,575,721 (285)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Publication ethics statement for issue 1-2018 / Кодекс профессиональной этики журнала «Военно-технический вестник», к выпуску № 1-2018 / Izjava o etičkom postupanju za br. 1-2018

Vojnotehnički Glasnik, 2018
The publication of an article in this peer reviewed journal is an essential model for the scientific journal Military Technical Courier. It is necessary to agree upon standards of expected ethical behavior for all parties involved in the act of ...
Nebojša N. Gaćeša
doaj  

REporting quality of PilOt randomised controlled trials in surgery (REPORTS): a methodological survey protocol

BMJ Open
Introduction The aim of this methodological review is to evaluate the completeness of reporting of surgical pilot and feasibility randomised trials as per the Consolidated Standards of Reporting Trials (CONSORT) extension to randomised pilot and ...
Lehana Thabane, Mohit Bhandari, Sameer Parpia, Keean Nanji, Sophia Zhang, Alex Thabane, Tyler McKechnie, Tania Kazi, Austine Wang, Aristithes G Doumouras, Cagla Eskicioglu   +10 more
doaj   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Protocol for a comparative cross-sectional study on characterisation of auditory impairment in sickle cell disease and sickle cell trait and its impact on health-related quality of life in Nigeria

BMJ Open
Introduction Sickle cell disease (SCD) and sickle cell traits (SCT) are genetically inherited red blood cell disorders common among people of African descent. Nigeria has a high prevalence of SCD, with a prevalence of 2.28%–3% and SCT, 25%–30%.
Obiageli Nnodu, Titus S Ibekwe, Christine Rogers, Lebogang Ramma   +3 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Catholic Hospital Ethics [PDF]

, 1972
This is the final Report of the Commission on Ethical and Religious Directives for Catholic Hospitals - a study commission established by the Catholic Theological Society of America in June, 1971.
Commission on Ethical and Religious Directives for Catholic Hospitals
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Developing a Writing Workshop for Clinician-Educators: A Synergistic Integration of Ethics, Rhetoric and Education Theories, and Social Science

MedEdPublish, 2017
Introduction: Clinician-educators often need specific direction in writing to publish their scholarly works. Faculty writing workshops and retreats, as well as helpful articles, address the "how-to" of writing but not the "pitfalls" of publishing.
B. Lee Ligon, Rachelle Weinstein, Satid Thammasitboon   +2 more
doaj  

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source