Results 81 to 90 of about 1,575,721 (285)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

RETRACTED : Mechanical and structural reliability based algorithm optimization

Journal of Materials and Engineering Structures, 2019
This article has been retracted at the request of the Editors-in-Chief, according to the Publication Ethics Policy and Publication Malpractice Statement.
Ahmed SAHLI, Sara SAHLI
doaj  

Ethics Requirement Score: new tool for evaluating ethics in publications

Einstein (São Paulo)
Objective To analyze ethical standards considered by health-related scientific journals, and to prepare the Ethics Requirement Score, a bibliometric index to be applied to scientific healthcare journals in order to evaluate criteria for ethics in ...
Lígia Gabrielle dos Santos, Ana Carolina da Costa e Fonseca, Claudia Giuliano Bica   +2 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

RETRACTED : Composite parameters analysis with boundary element method

Journal of Materials and Engineering Structures, 2019
This article has been retracted at the request of the Editors-in-Chief, according to the Publication Ethics Policy and Publication Malpractice Statement.
Ahmed SAHLI, Fatiha ARAB MOHAMED, Sara SAHLI   +2 more
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

RETRACTED : Influence parameters analysis in the gear helix correction

Journal of Materials and Engineering Structures, 2018
This article has been retracted at the request of the Editors-in-Chief, according to the Publication Ethics Policy and Publication Malpractice Statement. Please see : http://revue.ummto.dz/index.php/JMES/about/editorialPolicies#custom-2   This note is
Ossama BENOUIS, Ahmed SAHLI, Said KEBDANI, Sara SAHLI   +3 more
doaj  

Some ethical and legal considerations in the use of Web 2.0 [PDF]

, 2011
This chapter explores ethical and legal issues that need to be considered by health information professionals when using Web 2.0 technologies. It reviews how the Internet and the Web have affected standards of professional behaviour, and highlights the ...
Morgan, Peter
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

RETRACTED : Elastic-plastic analysis of reinforced composite materials

Journal of Materials and Engineering Structures, 2017
This article has been retracted at the request of the Editors-in-Chief, according to the Publication Ethics Policy and Publication Malpractice Statement. Please see : http://revue.ummto.dz/index.php/JMES/about/editorialPolicies#custom-2   This note is
Mohamed Rida SEBA, Said KEBDANI, Ahmed SAHLI, Sara SAHLI   +3 more
doaj