Results 111 to 120 of about 3,793,234 (227)
Nonequilibrium roughening transition in a simple model of fungal growth in 1+1 dimensions
We introduce a simple model of yeast-like growth of fungi colonies, which exhibits a continuous roughening transition far from equilibrium from a smooth ($\alpha = 0$) to rough phase ($\alpha = 1/2$) in 1+1 dimensions.
Jensen, Henrik Jeldtoft, Lopez, Juan M.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Peer review and in-depth interviews with publishers as a means of assessing quality of research monographs [PDF]
It has often been observed that evaluating scientific activity in the Humanities and in some of the Social Sciences needs to involve a study of monographs, as they are often the preferred mean of publication by scientists in these fields.
Giménez-Toledo, Elea, Román, Adelaida
core
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Following publication, concerns were raised regarding the peer-review process related to the publication of this article [...]
Parisa Vahidi Ferdowsi +3 more
doaj +1 more source

