Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
A Systematic Bibliometric Review Analysis of Research on the Use of Waste Rubber Tyres in Building and Construction Materials and Their Applications. [PDF]
Polymers (Basel)Castillo R +3 more
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
S-100B in acute ischemic stroke: a visualization of global hotspots. [PDF]
Int J Emerg MedGurijala S, Malik S, Ganti L.
europepmc +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
ChatGPT in Medical Education: Bibliometric and Visual Analysis.
JMIR Med EducZhang Y, Xie X, Xu Q.
europepmc +1 more source
Mapping the global intellectual landscape of inflammatory tumor microenvironment in colorectal cancer pathogenesis and prognostic research since this century. [PDF]
Discov OncolMu H +12 more
europepmc +1 more source
Card games are effective tools to enhance foundation year health and safety inductions
FEBS Open Bio, EarlyView.A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq +4 more
wiley +1 more source
Correction: Patient Safety of Perioperative Medication Through the Lens of Digital Health and Artificial Intelligence. [PDF]
JMIR Perioper Medeuropepmc +1 more source