Results 91 to 100 of about 421,104 (286)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Publics and prejudice in radio research [PDF]
, 2014 An invited essay on the question of what the success of shock radio in America tells us about the act of listening in public ...
Lacey, Kate
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Agriculture 4.0: Broadening Responsible Innovation in an Era of Smart Farming
Frontiers in Sustainable Food Systems, 2018 Agriculture is undergoing a new technology revolution supported by policy-makers around the world. While smart technologies, such as Artificial Intelligence, robotics, and the Internet of Things, could play an important role in achieving enhanced ...
David Christian Rose, Jason Chilvers
doaj +1 more source
Do companies reduce CSR disclosures during recessions? [PDF]
, 2012 Purpose: We investigate trends in prevalence and volume of CSR disclosure by the top 50 New Zealand listed companies from 2005 to 2010, i.e. from before until after the initial impact of the global financial crisis (GFC). Design/methodology/approach: We
de Villiers, Charl, Pinto, Sydelle
core +2 more sources
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Candomblé in Public: How Religious Rites Become Civil Technologies in Salvador, Brazil
Open TheologyIn 2019, right before arriving in Salvador, Brazil, to develop missionary activities, an international Protestant organization declared that this city – the center of the black culture in the country – was “known for its people’s belief in spirits and ...
de Paula Leandro
doaj +1 more source
Urban geography: urban growth machine [PDF]
, 2009 Urban growth machine is an influential thesis of urban politics that suggests the objective of growth unites otherwise pluralistic interests in relation to a city.
Rodgers, Scott
core
'Imagine if our cities talked to us': Questions about the making of 'responsive' places and urban publics [PDF]
, 2016 This book focuses on the surprising generative possibilities which digital and smart technologies offer media consumers, citizens, institutions and governments in making publics and places, across topics as diverse as Twitter audiences, ...Mary ...
Griffiths, O.
core +1 more source