Results 101 to 110 of about 421,104 (286)
Hepatology 20 (1994) 264-264.
Scripps Clinic La Jolla, California 92037 USA ( host institution ) +6 more
openaire +3 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Public funding, public knowledge, publication
The argument that publicly funded research should be publicly available is a valid one, but it cannot be the most important one in the discussion as to whether research should be freely accessible. The overriding argument is that freely accessible research optimises the scientific process as well as its 'translation' into societal benefits. Free access,
openaire +2 more sources
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
L’auteure adopte dans ce texte un angle nouveau dans le domaine de recherche sur les résidences d’artistes. S’éloignant du point de vue des artistes, elle se place du côté des centres d’art qui les accueillent afin de mieux appréhender les retombées de ...
Margot de Roquefeuil
doaj +1 more source
Landscape aesthetics: Assessing the general publics’ rural landscape preferences [PDF]
working paperThe central aim of this study was to gain greater insights into the factors that affect individuals’ preferences for a variety of landscape settings.
Howley, Peter
core
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Diasporic Film in Communities [PDF]
The Diasporic Film in Communities project set out to critically examine the role of Diasporic film culture in Diasporic communities. A case study approach was used to explore how three postcolonial publics (African-Caribbean, Chinese and South Asian ...
Malik, S
core
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source

