Results 51 to 60 of about 421,104 (286)

Talk, Ties, and Social Times: Unpacking the Duality of Networks and Futures

open access: yesSociologica
How is talk about what will, could, and should happen in the future shaped by networks of actors engaged in these conversations?  And how do conversations about imagined futures reshape social relations?
Ann Mische
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Impact of the variational assimilation of ground-based GNSS zenith total delay into AROME-Morocco model

open access: yesTellus: Series A, Dynamic Meteorology and Oceanography, 2020
The impact of assimilating zenith total delay (ZTD) observations from the Moroccan ground-based Global Navigation Satellite System (GNSS) network into the high-resolution operational model AROME-Morocco (2.5 km) is assessed over one month.
Fatima Zahra Hdidou   +5 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Archaeologies of Sound: Reconstructing Louis MacNeice’s Wartime Radio Publics [PDF]

open access: yes, 2015
This article approaches the problem of reconstructing the culturally situated audience experience of radio programming through the example of Louis MacNeice's wartime radio broadcasts, notably "Alexander Nevsky" and "Christopher Columbus".
Ian Whittington
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Why Youth (heart) Social Network Sites: The Role of Networked Publics in Teenage Social Life [PDF]

open access: yes, 2008
Part of the Volume on Youth, Identity, and Digital Media Social network sites like MySpace and Facebook serve as "networked publics." As with unmediated publics like parks and malls, youth use networked publics to gather, socialize with their peers, and ...
danah boyd
core  

Prepublication Publications

open access: yesSMU Law Review Forum, 2022
Many law professors now post essentially complete drafts of their articles on SSRN and/or on university-sponsored working paper websites prior to submitting those articles for journal review and possible publication. This “prepublication publication,” so to speak, is useful for both authors and their readers, but it raises some self-plagiarism issues ...
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy