Results 121 to 130 of about 2,527,653 (328)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Translator’s and Publisher’s Voices in the Contemporary Translations into Judeo-Spanish
Sefarad : Revista de Estudios Hebraicos y SefardíesJudeo-Spanish is the heritage language of Sephardic Jews and nowadays it is regarded as endangered. In recent years the interest in this language in places where the Sephardic live has been growing and this phenomenon has features of a postvernacular ...
Agnieszka August-Zarębska +1 more
doaj +1 more source
Lizenzverträge für elektronische Medien lesen lernen – Struktur und Auslegungsregeln
GMS Medizin – Bibliothek – Information, 2015 Licenses for electronic resources are often written in a small font size and still a couple of pages long. This article introduces rules of interpretation for vague clauses. German law regulating general terms and conditions is explained.
Grisse, Mareike
doaj +1 more source
An Optimised Investment Model of the Economics of Integrated Returns from CCS Deployment in the UK/UKCS [PDF]
, 2013 Publisher ...
Kasim, Sola, Kemp, Alexander G.
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Texas contest fiddling : moving the focus of contrast and change to inner variations [PDF]
, 2010 Publisher ...
Goertzen, Chris
core
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source