Results 141 to 150 of about 602,512 (247)

AI-Integrated Counseling Administration Quality and Organizational Support as Drivers of Early Risk Detection in Indonesian Schools. [PDF]

open access: yesF1000Res
Novebri N   +9 more
europepmc   +1 more source

Global Information Integrity [PDF]

open access: yes
Cover -- Guest editorial -- Internal communication and information integrity -- Knowing the value of information -- how can we teach our students to have analytical minds?
Smedley, Jo., Broady-Preston, Judith.
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Curcumin-Modified Selenium Nanoparticles Improve S180 Tumour Therapy in Mice by Regulating the Gut Microbiota and Chemotherapy [Expression of Concern]

open access: yesInternational Journal of Nanomedicine
Zhang R, Zhang W, Zhang Q, et al. Int J Nanomedicine. 2024;19:13653–13669. https://doi.org/10.2147/IJN.S476686 We, the Editors and Publisher of the International Journal of Nanomedicine, are issuing an Expressison of Concern for the published
Zhang R   +9 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

THE KNOWLEDGE MANAGEMENT – NECESSITY FOR THE MODERNIZATION OF THE ORGANIZATIONS [PDF]

open access: yes
If individuals and technologies can harmonize their intelligence under various forms, only the intelligent organizations will have the capacity to transform and coordinate these abilities for their own advantage by using informational technologies, by ...
Adina BĂLAN
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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