Results 201 to 210 of about 602,512 (247)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Retraction Note: Improving stroke risk prediction by integrating XGBoost, optimized principal component analysis, and explainable artificial intelligence. [PDF]

BMC Med Inform Decis Mak
Mochurad L, Babii V, Boliubash Y, Mochurad Y.   +3 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Correction: Development and validation of a deep learning-based automatic detection and classification model for femoral neck fractures using hip imaging: a retrospective multicenter diagnostic study. [PDF]

Front Med (Lausanne)
Han X, Zhu Y, Chen S, Peng L, Xiao Y, Wu H, Qu Z.   +6 more
europepmc   +1 more source

EXPRESSION OF CONCERN: A Newly Identified 45‐kDa JAK2 Variant with an Altered Kinase Domain Structure Represents a Novel Mode of JAK2 Kinase Inhibitor Resistance

Molecular Oncology, EarlyView.
wiley   +1 more source

Erratum to "World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update - IV - A quality appraisal with the AGREE II instrument" [World Allergy Organ J 15(2) (February 2022) 100613]. [PDF]

World Allergy Organ J
Strózyk A, Ruszczynski M, Horvath A, Dahdah L, Fiocchi A, Nowak-Węgrzyn A, Shamir R, Spergel J, Vandenplas Y, Venter C, Szajewska H, WAO DRACMA guideline group.   +11 more
europepmc   +1 more source

Correction: LSML-SF: a lightweight stacked ML approach for spreading factor allocation in mobile IoT LoRaWAN networks. [PDF]

Front Artif Intell
Farhad A, Lodhi MA, Nisar F, Hadi HJ, Ahmad N, Ladan M.   +5 more
europepmc   +1 more source

Expression of Concern. [PDF]

J Enzyme Inhib Med Chem
europepmc   +1 more source