Results 31 to 40 of about 20,333 (260)
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Starting from a description of today’s Swedish book market, which has seen a steady decline of French and other Romance languages as source languages for translated literature, this article investigates the importance of independent publishers for the ...
Andreas Hedberg
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
"Book of the Open Lithuania" - the first ten years
The Publishing program of the Lithuanian Open Foundation (Soros Foundation) has been working for more than ten years. The specialists of the Faculties of Communication and Philosophy had done a research of the activity of the Publishing program in 2001 ...
Julija Zinkevičienė +1 more
doaj +1 more source
Literature for children in the Publishing House of I. P. Ladyzhnikov (Berlin, 1920–1930)
The purpose of the article is to fill the gap in the study of such an aspect of the activities of Russian-language foreign publishing houses as the release of literature for children and youth.
A. О. Anisimov
doaj +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
“BOOK PUBLISHING IN RUSE, 1864–1944”: BIBLIOGRAPHICAL INDEX
The text is a review of the bibliographic index “Book Publishing in Ruse, 1864–1944”, published by the Regional Library “Lyuben Karavelov”. A chronicle of the books printed in the city for the indicated period, the index outlines the development of ...
Valentina Mitkova
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source

