Results 31 to 40 of about 5,098,461 (303)
Implementation of a Hardware/Software Platform for Real-Timedata-Intensive Applications in Hazardous Environments [PDF]
, 1996 Real-Time Technology and Applications Symposium. Brookline, MA, USA, 10-12 Oct. 1996In real-time data-intensive applications, the simultaneous achievement of the required performance and determinism is a difficult issue to address, mainly due to the time
García-Martínez, Alberto +2 more
core +1 more source
Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Advanced Science, EarlyView.Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
Geocarto InternationalWe expound on a hydrographic and geophysical survey in the south of the Archipelago of San Andres, Providencia, and Santa Catalina (ASAPSC) in the Colombian Caribbean Sea. In 2017 and 2018, high-resolution data were acquired from the Caribbean Center for
Karem Oviedo-Prada +9 more
doaj +1 more source
Engineering Proceedings, 2023 GNSS systems allow precise resolution of the geodetic positioning problem through advanced techniques of GNSS observation processing (PPP or relative positioning).
Paola Barba +5 more
doaj +1 more source
Efectos reales de impulsos tecnológicos: el caso de Puerto Rico
Estudios Económicos de El Colegio de México, 2021 Este trabajo estudia los efectos de impulsos tecnológicos reflejados en cambios anticipados y no anticipados en la productividad factorial total sobre las fluctuaciones macroeconómicas en Puerto Rico. Con estos fines, se emplean técnicas bayesianas para estimar los parámetros del proceso tecnológico de un modelo de equilibrio general dinámico y ...
Emanuelle A. Alemar +1 more
openaire +2 more sources
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
OENO One, 2023 Brandy is a spirit obtained from distilled wine that has an alcohol content equal to or greater than 36 % ABV (Alcohol by Volume). It undergoes an ageing process in oak wood casks with a capacity of up to 1000 L for a minimum of six months.
Daniel Butron +4 more
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Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields
Advanced Science, EarlyView.Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Jiaxuan Cheng +71 more
wiley +1 more source
Foods, 2022 Brandy is a unique alcoholic beverage obtained from wine distillates. Numerous studies have been published on its physicochemical traits and the effect of certain elaboration variables on them, but not many studies have been carried out from a sensory ...
María Guerrero-Chanivet +6 more
doaj +1 more source
Gephyrin Neurological Autoimmunity
Annals of Neurology, EarlyView.Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano +10 more
wiley +1 more source