Results 1 to 10 of about 93,759 (165)
Spontaneous regression of metastatic squamous cell lung cancer
Key Clinical Message Spontaneous regression (SR) of cancer is a rare but confirmed spectacular phenomenon, and it is even rarer in the context of advanced NSCLC. It is essential to understand this phenomenon in order to elucidate the nature of neoplastic
Miguel Ariza‐Prota +2 more
doaj +2 more sources
Abstract Intravenous β‐lactam antibiotics remain a cornerstone in the management of bacterial infections due to their broad spectrum of activity and excellent tolerability. β‐lactams are well established to display time‐dependent bactericidal activity, where reductions in bacterial burden are directly associated with the time that free drug ...
Lisa T. Hong +16 more
wiley +1 more source
Abstract Introduction Spirometry is associated with several diagnostic difficulties, and as a result, misdiagnosis of chronic obstructive pulmonary disease (COPD) occurs. This study aims to investigate how random forest (RF) can be used to improve the existing clinical FVC and FEV1 reference values in a large and representative cohort of the general ...
Kris Kristensen +7 more
wiley +1 more source
Regulation Networks Driving Vasculogenic Mimicry in Solid Tumors
Vasculogenic mimicry (VM) is a mechanism whereby cancer cells form microvascular structures similar to three-dimensional channels to provide nutrients and oxygen to tumors.
Olga N. Hernández de la Cruz +7 more
doaj +1 more source
Dietary phosphate restriction prevents the appearance of sarcopenia signs in old mice
Abstract Background Sarcopenia is defined by the progressive and generalized loss of muscle mass and function associated with aging. We have previously proposed that aging‐related hyperphosphataemia is linked with the appearance of sarcopenia signs. Because there are not effective treatments to prevent sarcopenia, except for resistance exercise, we ...
Elena Alcalde‐Estévez +8 more
wiley +1 more source
Metallodrugs: an approach against invasion and metastasis in cancer treatment
In this review, we examine the use of metallodrugs for cancer treatment, focussing on the advances in this type of therapy and the importance of these compounds, with emphasis on Pt, Ru, Au, Zn, and Cu as antimetastatic agents. In addition, we discuss the different mechanisms of action by which metallodrugs exert their therapeutic effects.
Mauricio M. González‐Ballesteros +2 more
wiley +1 more source
Fetal movements: the origin of human behaviour
The study of the onset and ontogeny of human behaviour has made it clear that a multitude of fetal movement patterns are spontaneously generated, and that there is a close association between activity and the development of peripheral and central structures.
Christa Einspieler +2 more
wiley +1 more source
Abstract Research in China has been advancing over the past decade with increasing investments from government and private entities. Collaboration with Chinese investigators and those in the United States has also increased as reflected in the growth of scientific papers with Chinese authors. Collaborations are more commonly based on faculty‐to‐faculty
Joseph C. Kolars, Qimin Zhan
wiley +1 more source
EL REGULADOR DE TRASMEMBRANA DE FIBROSIS QUÍSTICA (CFTR) DISFUNCIONAL Y SUS EFECTOS EXTRAPULMONARES
El daño del regulador de transmembrana de fibrosis quística (CFTR) puede causar una enfermedad grave fuera de los pulmones. El canal de cloruro (Cl-) ha sido el más estudiado, sin embargo, el bicarbonato (HCO3 -) tiene un rol muy importante en el ...
María Lina Boza
doaj +1 more source
El leiomioma primario de pulmón es un tumor benigno raro, de origen mesodérmico, que representa aproximadamente el 2 % de todos los tumores benignos de pulmón. Desde que fue descrito por primera vez por Forkel en 1910, se han reportado al menos 150 casos
Ricardo Adolfo Zapata-González +3 more
doaj +1 more source

