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Pulmonary Alveolar Proteinosis [PDF]
Pulmonary alveolar proteinosis (PAP) is a disease of alveolar accumulation of phospholipoproteinaceous material that results in gas exchange impairment leading to dyspnea and alveolar infiltrates.
Sandeep M Patel +3 more
doaj +9 more sources
Pulmonary alveolar proteinosis [PDF]
Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disease characterised by alveolar accumulation of surfactant. It may result from mutations in surfactant proteins or granulocyte macrophage-colony stimulating factor (GM-CSF) receptor genes, it may
B. Crestani +7 more
doaj +12 more sources
Primary pulmonary alveolar proteinosis [PDF]
Introduction. Pulmonary alveolar proteinosis is an uncommon disease characterized by the accumulation of surfactant proteins and phospholipids within the alveolar spaces. Acquired disease can be idiopathic (primary) and secondary.
Šarac Sanja +5 more
doaj +5 more sources
Pulmonary alveolar proteinosis [PDF]
Pulmonary alveolar proteinosis (PAP) is a syndrome characterized by the accumulation of alveolar surfactant and dysfunction of alveolar macrophages. PAP results in progressive dyspnoea of insidious onset, hypoxaemic respiratory failure, secondary infections and pulmonary fibrosis.
Bruce C Trapnell +2 more
exaly +10 more sources
Anaesthesia for serial whole-lung lavage in a patient with severe pulmonary alveolar proteinosis: a case report [PDF]
Introduction Pulmonary alveolar proteinosis is a rare condition that requires treatment by whole-lung lavage. We report a case of severe pulmonary alveolar proteinosis and discuss a safe and effective strategy for the anaesthetic management of patients ...
Webb Stephen T +3 more
doaj +6 more sources
PULMONARY ALVEOLAR PROTEINOSIS
Excerpt Pulmonary alveolar proteinosis was first described by Rosen et al. in June, 1958.1We have had the opportunity to observe a patient with this disease, and wish to report the clinical, labora...
Leldon P. Pitt
+11 more sources
The Novel Use of Daratumumab in the Treatment of Refractory Autoimmune Pulmonary Alveolar Proteinosis. [PDF]
We present a case of refractory autoimmune pulmonary alveolar proteinosis (aPAP) successfully treated with Daratumumab, a novel CD‐38 monoclonal antibody (mAb). ABSTRACT Autoimmune pulmonary alveolar proteinosis (aPAP) is caused by circulating anti‐granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) auto‐antibodies that impair alveolar macrophage
Strong A +4 more
europepmc +2 more sources
A New Era in the Treatment of Autoimmune Pulmonary Alveolar Proteinosis. [PDF]
Respirology, Volume 30, Issue 6, Page 463-465, June 2025.
Tazawa R, Nakata K.
europepmc +2 more sources
[Pulmonary alveolar proteinosis]. [PDF]
Figure 1. A 26-year-old man presented with nonproductive cough and exertional dyspnea. Physical examination disclosed acrocyanosis. Chest radiography showed patchy alveolar and interstitial disease in a perihilar “batwing” distribution (Panel A). High-resolution computed tomography of the chest (Panel B) revealed extensive bilateral air-space disease ...
S. Jouneau +9 more
+8 more sources
Unsuspected pulmonary alveolar proteinosis in a patient with acquired immunodeficiency syndrome: a case report [PDF]
Introduction Diffuse lung infiltrates are a common finding in patients with acquired immunodeficiency syndrome and causes range from infectious processes to malignancies or interstitial lung diseases.
Niazi Masooma +3 more
doaj +4 more sources

