Results 1 to 10 of about 8,512 (164)

Primary pulmonary alveolar proteinosis [PDF]

Vojnosanitetski Pregled, 2012
Introduction. Pulmonary alveolar proteinosis is an uncommon disease characterized by the accumulation of surfactant proteins and phospholipids within the alveolar spaces. Acquired disease can be idiopathic (primary) and secondary.
Šarac Sanja, Milić Rade, Zolotarevski Lidija, Aćimović Slobodan, Tomić Ilija, Plavec Goran   +5 more
doaj   +3 more sources

Therapeutic Whole Lung Lavage for Pulmonary Alveolar Proteinosis: Technique With Continuous Video‐Enabled Double Lumen Endotracheal Tube [PDF]

Respirology Case Reports
Therapeutic whole lung lavage with a continuous video‐enabled double‐lumen endotracheal tube improves the safety of therapeutic whole lung lavage in autoimmune pulmonary alveolar proteinosis.
Kevin Davidson
doaj   +2 more sources

Whole Lung Lavage in Autoimmune Pulmonary Alveolar Proteinosis: Unique Challenges in a Resource‐Limited Setting [PDF]

Clinical Case Reports
Autoimmune pulmonary alveolar proteinosis (PAP) is characterized by antibodies to granulocyte–macrophage colony‐stimulating factor (GM‐CSF), alveolar macrophage dysfunction, and surfactant accumulation.
Ashesh Dhungana, Buddhi Sagar Lamichhane, Prajowl Shrestha, Deepa Kumari Shrestha, Ritamvara Oli, Shreya Dhungana, Pratibha Bista   +6 more
doaj   +2 more sources

CD40LG-associated X-linked Hyper-IgM Syndrome (XHIGM) with pulmonary alveolar proteinosis: a case report

BMC Pediatrics, 2023
Background D40LG-associated X-linked hyper-IgM syndrome with pulmonary alveolar proteinosis has rarely been reported, and its genotype-phenotypic correlation remains elusive. Case presentation We describe a five-month-old boy with CD40LG mutation (c.516T 
Hong-bo Xu, Mao-qiang Tian, Yong-hua Bai, Xiao Ran, Lei Li, Yan Chen   +5 more
doaj   +1 more source

Autoimmune pulmonary alveolar proteinosis successfully treated with lung lavage in an adolescent patient: a case report

Journal of Medical Case Reports, 2021
Background Pulmonary alveolar proteinosis is a rare interstitial lung disease characterized by accumulating surfactant materials in the alveoli. The autoimmune form is by far the most common in adults, while in the pediatric age group, the vast majority ...
Abdalla Mohmed Alasiri, Reem Abdullah Alasbali, Meaad Ali Alaqil, Aishah Marei Alahmari, Nouf Dagash Alshamrani, Rabab Nasir Badri   +5 more
doaj   +1 more source

Pulmonary Alveolar Proteinosis: Case Report

Архивъ внутренней медицины, 2020
Pulmonary alveolar proteinosis is a rare disease of the lungs due to abnormal surfactant metabolism with accumulation of pathological protein lipid substance in the lumen of alveoli.Presented case of idiopathic alveolar proteinosis is characterized by ...
N. A. Karoli, E. E. Arhangelskaja, O. T. Zarmanbetova   +2 more
doaj   +1 more source

Interstitial lung disease as a late complication of pulmonary alveolar proteinosis

Radiology Case Reports, 2019
Pulmonary alveolar proteinosis is a rare condition characterized by accumulation of intra-alveolar surfactant. Here, we report a case of interstitial lung disease which developed over the years in a patient with pulmonary alveolar proteinosis.
Alexandre Semionov, MD, PhD, John Kosiuk, MD   +1 more
doaj   +1 more source

Clinical biological and genetic heterogeneity of the inborn errors of pulmonary surfactant metabolism [PDF]

, 2001
Pulmonary surfactant is a multimolecular complex located at the air-water interface within the alveolus to which a range of physical (surface-active properties) and immune functions has been assigned. This complex consists of a surface-active lipid layer
Clements JA, Crouch E, deMello DE, Dirksen U, Doyle IR, Fisher JH, Floros J, Glasser SW, Green D, Hawgood S, Ikegami M, Ikegami M, Ikegami M, Kitamura T, Kresch MJ, Madan T, Mahut B, Mason RJ, Myrianthopoulos NC, Nogee LM, Pilot-Matias TJ, Power JHT, Prakash UBS, Reed JA, Robertson B, Rosen SH, Stoll BJ, Tredano M, Vorbroker DK, Wang J-Y   +29 more
core   +1 more source

A newly identified novel variant in the CSF2RA gene in a child with pulmonary alveolar proteinosis: a case report

Journal of Medical Case Reports, 2017
Background The congenital form of pulmonary alveolar proteinosis due to colony stimulating factor 2 receptor alpha gene mutations is a rare disease with only a few cases reported worldwide.
Adel S. Al-Haidary, Wadha Alotaibi, Sami A. Alhaider, Suhail Al-Saleh   +3 more
doaj   +1 more source

Mavrilimumab, a fully human granulocyte-macrophage colony-stimulating factor receptor α monoclonal antibody: long-term safety and efficacy in patients with rheumatoid arthritis [PDF]

, 2018
Objective: Mavrilimumab, a human monoclonal antibody, targets granulocyte-macrophage colony-stimulating factor receptor alpha. We report mavrilimumab long-term safety and efficacy in rheumatoid arthritis patients in two phase IIb studies (1071, 1107 ...
Achuthan, Akagawa, Aletaha, Aletaha, Antoniu, Avci, Berghen, Borg, Borie, Brown, Buch, Burmester, Burmester, Calisto, Cella, Chen, Cook, Cornish, Cottin, Crotti, Dawson, Felson, Fleetwood, Fries, Greven, Guo, Hamilton, Jaguin, Kelly, Khan, Lazaro, Listing, Minter, Prevoo, Shaw, Shibata, Singh, Tsuchiya, Van der Heijde, Van Gestel, Van Onna, Ware, Weinblatt, Yoshida, Zhan   +44 more
core   +1 more source