Results 11 to 20 of about 8,581 (204)
Pulmonary Alveolar Proteinosis [PDF]
Canadian Respiratory Journal, 2012 Pulmonary alveolar proteinosis (PAP) is a disease of alveolar accumulation of phospholipoproteinaceous material that results in gas exchange impairment leading to dyspnea and alveolar infiltrates.
Sandeep M Patel +3 more
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Pulmonary alveolar proteinosis [PDF]
European Respiratory Review, 2011 Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disease characterised by alveolar accumulation of surfactant. It may result from mutations in surfactant proteins or granulocyte macrophage-colony stimulating factor (GM-CSF) receptor genes, it may
B. Crestani +7 more
doaj +8 more sources
Congenital Pulmonary Alveolar Proteinosis [PDF]
Case Reports in Pediatrics, 2013 Pulmonary alveolar proteinosis (PAP) is a rare syndrome characterized by pulmonary surfactant accumulation within the alveolar spaces. It occurs with a reported prevalence of 0.1 per 100,000 individuals. Two clinically different pediatric types have been
Saber Hammami +5 more
doaj +3 more sources
A Rare Case of Pulmonary Alveolar Proteinosis Superimposed by Severe COVID-19 Pneumonia: Case Report. [PDF]
Respirol Case RepThis report presents a rare case of pulmonary alveolar proteinosis (PAP) in a young male who subsequently developed COVID‐19. It highlights the critical importance of integrating clinical and radiological precision in diagnosing lung diseases with overlapping imaging features and underscores the rapid deterioration observed when PAP is complicated by ...
El Mawla Z, Al Mulki J, Hassoun M.
europepmc +2 more sources
Pulmonary Alveolar Proteinosis Complicated by Invasive <i>Streptococcus pneumoniae</i> Infection Requiring Extracorporeal Membrane Oxygenation: A Case Report. [PDF]
Acute Med SurgA rare case of autoimmune pulmonary alveolar proteinosis complicated by invasive Streptococcus pneumoniae infection was successfully managed with veno‐venous ECMO. ECMO enabled timely whole lung lavage during recovery from septic shock, which yielded atypical yellowish‐brown fluid likely reflecting infection and led to clinical improvement.
Mizusawa U +8 more
europepmc +2 more sources
Rapid Serological Detection of Anti-GM-CSF Autoantibodies in Autoimmune Pulmonary Alveolar Proteinosis Using a Novel Immunochromatographic Test. [PDF]
RespirologyWe developed a novel ICT with high clinical performance that can distinguish APAP patients from those with other pulmonary diseases. The rapid and simple detection of GMAbs in serum provided a new practical method for the diagnosis of APAP. See related editorial ABSTRACT Background and Objectives Anti‐GM‐CSF autoantibodies (GMAbs) are essential ...
Narita C +10 more
europepmc +2 more sources
A Hereditary Pulmonary Alveolar Proteinosis Caused by a Novel Hemizygous Variation of the CSF2RA Gene Case Report and Literature Review. [PDF]
Mol Genet Genomic MedThis paper describe a 3‐year‐old girl with Turner syndrome who presented with recurrent cough and dyspnea and was diagnosed with hereditary PAP. Genetic analysis revealed a novel hemizygous mutation in the CSF2RA gene (NM_000402.4:c.200_204del, p.Asn67SerfsTer8), which was confirmed as a de novo pathogenic variant and had not been reported previously ...
Chen Q +6 more
europepmc +2 more sources
Pulmonary alveolar proteinosis [PDF]
Respirology, 2020 ABSTRACTPAP is an ultra‐rare disease in which surfactant components, that impair gas exchange, accumulate in the alveolae. There are three types of PAP. The most frequent form, primary PAP, includes autoimmune PAP which accounts for over 90% of all PAP, defined by the presence of circulating anti‐GM‐CSF antibodies.
Jouneau, Stéphane +2 more
openaire +3 more sources
Pulmonary alveolar proteinosis [PDF]
Chronic Respiratory Disease, 2006 Pulmonary alveolar proteinosis is a rare syndrome characterized by intra-alveolar accumulation of surfactant components and cellular debris, with minimal interstitial inflammation or fibrosis. The condition has a variable clinical course, from spontaneous resolution to respiratory failure and death due to disease progression or superimposed infections.
O C, Ioachimescu, M S, Kavuru
openaire +2 more sources
Journal of Medical Case Reports, 2008 Introduction Pulmonary alveolar proteinosis is a rare condition that requires treatment by whole-lung lavage. We report a case of severe pulmonary alveolar proteinosis and discuss a safe and effective strategy for the anaesthetic management of patients ...
Webb Stephen T +3 more
doaj +1 more source