Results 21 to 30 of about 61,025 (285)

Pulmonary alveolar proteinosis after lung transplantation

Respirology Case Reports, 2020
We report the case of a 69‐year‐old man five‐month post double lung transplant for idiopathic pulmonary fibrosis (IPF) who presented with progressive breathlessness, loss of lung function, and diffuse ground glass shadowing on the chest computed ...
Chandima Divithotawela, Simon H. Apte, Maxine E. Tan, Tharushi A. De Silva, Daniel C. Chambers   +4 more
doaj   +2 more sources

Pulmonary and Systemic Toxicity in a Rat Model of Pulmonary Alveolar Proteinosis Induced by Indium-Tin Oxide Nanoparticles

International Journal of Nanomedicine, 2022
Nan Liu,1 Yi Guan,1 Chunling Zhou,2 Yongheng Wang,1 Zhanfei Ma,3 Sanqiao Yao1,4 1School of Public Health, North China University of Science and Technology, Tangshan, 063210, Hebei, People’s Republic of China; 2Baoding Center for Disease Control and ...
Liu N, Guan Y, Zhou C, Wang Y, Ma Z, Yao S   +5 more
doaj   +2 more sources

Acute pulmonary alveolar proteinosis due to exposure to cotton dust

Lung India, 2009
Secondary pulmonary alveolar proteinosis (PAP) is rare but may occur in association with malignancy, certain infections, and exposure to inorganic or organic dust and some toxic fumes.
Thind Gurcharan
doaj   +2 more sources

Whole Lung Lavage in Autoimmune Pulmonary Alveolar Proteinosis: Unique Challenges in a Resource‐Limited Setting [PDF]

Clinical Case Reports
Autoimmune pulmonary alveolar proteinosis (PAP) is characterized by antibodies to granulocyte–macrophage colony‐stimulating factor (GM‐CSF), alveolar macrophage dysfunction, and surfactant accumulation.
Ashesh Dhungana, Buddhi Sagar Lamichhane, Prajowl Shrestha, Deepa Kumari Shrestha, Ritamvara Oli, Shreya Dhungana, Pratibha Bista   +6 more
doaj   +2 more sources

Pulmonary Alveolar Proteinosis in a Dog [PDF]

Journal of Veterinary Internal Medicine, 2000
Deborah C. Silverstein, Craig Greene, Christopher Gregory, S. Lucas, Jane Quandt   +4 more
openalex   +4 more sources

Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis

Nature Communications, 2018
Pulmonary alveolar proteinosis (PAP) is associated with defective macrophage clearance of surfactant. Here, the authors show that patients with PAP have altered cholesterol-to-phospholipid ratio in their surfactant, and that more importantly, statin ...
Cormac McCarthy, Elinor Lee, James P. Bridges, Anthony Sallese, Takuji Suzuki, Jason C. Woods, Brian J. Bartholmai, Tisha Wang, Claudia Chalk, Brenna C. Carey, Paritha Arumugam, Kenjiro Shima, Elizabeth J. Tarling, Bruce C. Trapnell   +13 more
doaj   +2 more sources

Inhaled recombinant GM-CSF reduces the need for whole lung lavage and improves gas exchange in autoimmune pulmonary alveolar proteinosis patients

European Respiratory Journal, 2023
Graphical abstract Overview of the study. aPAP: autoimmune pulmonary alveolar proteinosis; rGM-CSF: recombinant granulocyte–macrophage colony-stimulating factor; WLL: whole lung lavage; AE: adverse event; SAE: serious adverse event.
I. Campo, B. Carey, Elena Paracchini, Zamir Kadija, Annalisa De Silvestri, G. Rodi, Mara De Amici, Cristina Torre, M. Zorzetto, Matthias Griese, Federica Meloni, A. Corsico, Bruce C. Trapnell, F. Mariani   +13 more
semanticscholar   +1 more source

Infections in autoimmune pulmonary alveolar proteinosis: a large retrospective cohort

Thorax, 2023
Background Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare disease, predisposing to an increased risk of infection. A complete picture of these infections is lacking.
Axelle Mabo, Raphaël Borie, L. Wémeau-Stervinou, Y. Uzunhan, E. Gomez, G. Prévôt, M. Reynaud-Gaubert, J. Traclet, E. Bergot, J. Cadranel, Sylvain Marchand-Adam, Anne Bergeron, E. Blanchard, B. Bondue, Philippe Bonniaud, A. Bourdin, Pierre-Régis Burgel, S. Hirschi, C. Marquette, S. Quêtant, Hilario Nunes, C. Chenivesse, B. Crestani, Yoann Guirriec, Delphine Monnier, Cédric Ménard, P. Tattevin, V. Cottin, David Luque Paz, S. Jouneau   +29 more
semanticscholar   +1 more source

CD40LG-associated X-linked Hyper-IgM Syndrome (XHIGM) with pulmonary alveolar proteinosis: a case report

BMC Pediatrics, 2023
Background D40LG-associated X-linked hyper-IgM syndrome with pulmonary alveolar proteinosis has rarely been reported, and its genotype-phenotypic correlation remains elusive. Case presentation We describe a five-month-old boy with CD40LG mutation (c.516T 
Hong-bo Xu, Mao-qiang Tian, Yong-hua Bai, Xiao Ran, Lei Li, Yan Chen   +5 more
doaj   +1 more source

Nebulised granulocyte–macrophage colony-stimulating factor (GM-CSF) in autoimmune pulmonary alveolar proteinosis: a systematic review and meta-analysis

European Respiratory Review, 2023
Background: Autoimmune pulmonary alveolar proteinosis (aPAP) results from impaired macrophage-mediated clearance of alveolar surfactant lipoproteins.
M. Munsif, Duncan Sweeney, Tracy L. Leong, Rob G. Stirling   +3 more
semanticscholar   +1 more source