Highlights of the Brazilian Thoracic Association guidelines for interstitial lung diseases [PDF]
, 2012 Interstitial lung diseases (ILDs) are heterogeneous disorders, involving a large number of conditions, the approach to which continues to pose an enormous challenge for pulmonologists.
Aidé, Miguel Abidon +24 more
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Proceedings: Regenerative Medicine for Lung Diseases: A CIRM Workshop Report. [PDF]
, 2017 The mission of the California Institute of Regenerative Medicine (CIRM) is to accelerate treatments to patients with unmet medical needs. In September 2016, CIRM sponsored a workshop held at the University of California, Los Angeles, to discuss ...
DeWitt, Natalie D +2 more
core +1 more source
Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar Proteinosis.
New England Journal of Medicine, 2020 BACKGROUND Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare disease characterized by progressive surfactant accumulation and hypoxemia. It is caused by disruption of granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling, which ...
B. Trapnell +18 more
semanticscholar +1 more source
Rituximab therapy in pulmonary alveolar proteinosis improves alveolar macrophage lipid homeostasis [PDF]
, 2012 Rationale Pulmonary Alveolar Proteinosis (PAP) patients exhibit an acquired deficiency of biologically active granulocyte-macrophage colony stimulating factor (GM-CSF) attributable to GM-CSF specific autoantibodies. PAP alveolar macrophages are foamy,
Barna, Barbara P +7 more
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Journal of International Medical Research, 2022 Pulmonary alveolar proteinosis (PAP) is a rare respiratory system disorder. Patients with PAP are at risk for a wide variety of secondary infections. This current case report describes a patient with PAP complicated by tuberculosis.
Guangtao Fan +3 more
doaj +1 more source
Innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice [PDF]
, 2012 Acute exacerbations of pulmonary fibrosis are characterized by rapid decrements in lung function. Environmental factors that may contribute to acute exacerbations remain poorly understood.
AG Heppleston +55 more
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Pulmonary Alveolar Proteinosis in an AIDS Patient without Concurrent Pulmonary Infection
Canadian Respiratory Journal, 1995 Patients with acquired immunodeficiency syndrome (AIDS) are potentially at increased risk for developing secondary pulmonary alveolar proteinosis because of underlying immunosuppression and frequent opportunistic lung infections. This condition. however,
Allen T Liu +4 more
doaj +1 more source
Proteinose alveolar congénita.
Acta Médica Portuguesa, 2005 Pulmonary Alveolar Proteinosis (PAP) is a rare entity characterized by the intra-alveolar accumulation of proteinaceous PAS positive and diastase resistant material. Its pathogenesis remains unclear, although a surfactant protein B deficiency and changes
Susana Pissarra +3 more
doaj +1 more source
European Respiratory JournalBackground Pulmonary alveolar proteinosis (PAP) is a rare syndrome caused by several distinct diseases leading to progressive dyspnoea, hypoxaemia, risk of respiratory failure and early death due to accumulation of proteinaceous material in the lungs ...
Cormac McCarthy +21 more
semanticscholar +1 more source
Von Hippel-Lindau protein is required for optimal alveolar macrophage terminal differentiation, self-renewal, and function [PDF]
, 2018 The rapid transit from hypoxia to normoxia in the lung that follows the first breath in newborn mice coincides with alveolar macrophage (AM) differentiation.
Brandi, Paola +12 more
core +4 more sources