Results 71 to 80 of about 8,581 (204)

Pulmonary alveolar proteinosis: a rare pulmonary toxicity of sirolimus. [PDF]

, 2007
Transpl Int. 2007 Mar;20(3):291-6. Pulmonary alveolar proteinosis: a rare pulmonary toxicity of sirolimus. Pedroso SL, Martins LS, Sousa S, Reis A, Dias L, Henriques AC, Sarmento AM, Cabrita A.
CABRITA, A., DIAS, L., HENRIQUES, A.C., Martins, La Salete, PEDROSO, S.L., REIS, A., SARMENTO, A.M., SOUSA, S.   +7 more
core   +1 more source

Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis [PDF]

, 2015
Pneumonia is a major cause of mortality worldwide and a serious problem in critical care medicine, but the immunophysiological processes that confer either protection or morbidity are not completely understood. We show that in response to lung infection,
Ali, Muhammad, Chen, John W., Chousterman, Benjamin G., Gerhardt, Louisa M.S., Hilgendorf, Ingo, Iwamoto, Yoshiko, Nahrendorf, Matthias, Quach, Tam D., Robbins, Clinton S., Rothstein, Thomas L., Swirski, Filip K., Theurl, Igor, Weber, Georg F., Weissleder, Ralph   +13 more
core   +1 more source

Epithelial–Mesenchymal Transition in Human Alveolar Cells Exposed to Indium Chloride

Journal of Applied Toxicology, Volume 45, Issue 11, Page 2353-2362, November 2025.
ABSTRACT For workers in the industry, occupational exposure to indium compounds induces pulmonary disorders, such as interstitial pneumonia. Moreover, lung cancer has been reported in both humans and rodents exposed to indium compounds by inhalation. However, the biological mechanism underlying indium‐induced disorders is poorly understood.
Eiki Kimura, Sharif Ahmed, Haijiao Chen, Yusuke Hiraku   +3 more
wiley   +1 more source

Lung Lavage Cell Profiles in Diffuse Lung Disease [PDF]

, 2010
The standard armamentarium of tests that are used by pulmonologist are laboratory tests, pulmonary function tests, different radiological techniques (conventional chest-X rays, HRCT scans, etc) and pathohistological analyses of biopsies.
Silvana Smojver-Ježek, Tatjana Peroš-Golubičić   +1 more
core   +1 more source

Early IL‐1 Inhibition in Still's Disease: A Window of Opportunity for Improving Outcomes

ACR Open Rheumatology, Volume 7, Issue 10, October 2025.
Objective Still's disease is a complex, multisystemic disorder requiring prompt diagnosis and treatment. This study provides a general assessment of a Still's disease cohort aiming to evaluate the efficacy of early intervention with interleukin‐1 inhibitors (IL‐1i) in achieving clinical inactive disease (CID) and reducing glucocorticoid use in patients
Sara Bindoli, Cristina Cadore, Irina Guidea, Andrea Doria, Roberta Ramonda, Paolo Sfriso   +5 more
wiley   +1 more source

Niche signals and transcription factors involved in tissue-resident macrophage development [PDF]

, 2018
Tissue-resident macrophages form an essential part of the first line of defense in all tissues of the body. Next to their immunological role, they play an important role in maintaining tissue homeostasis. Recently, it was shown that they are primarily of
Bonnardel, Johnny, Guilliams, Martin, T'Jonck, Wouter   +2 more
core   +2 more sources

The Paradox of Metachronous Lipoid Pneumonia

Respirology Case Reports, Volume 13, Issue 9, September 2025.
This is a case of recurrent exogenous lipoid pneumonia in a single patient caused by multiple unrelated substances. This case underscores the diagnostic value of radiologic patterns, the significance of meticulous exposure history, and the necessity of contemplating alternative aetiologies in patients with new infiltrates during cancer therapy ...
Haruki Kobayashi
wiley   +1 more source

Phase 1b randomized, double-blind study of namilumab, an anti-granulocyte macrophage colony-stimulating factor monoclonal antibody, in mild-to-moderate rheumatoid arthritis [PDF]

, 2017
Change from baseline in swollen (a) and tender (b) joint counts. *Error bars show upper SE for placebo and lower SE for namilumab. SE standard error, SJC swollen joint count, TJC tender joint count.
A. Batalov, AD Cook, AD Cook, AD Cook, AE Nieuwenhuijze van, AJ Fleetwood, AK Ulfgren, AM Gestel van, B. Souberbielle, BC Trapnell, BC Trapnell, BP Hazenberg, C Fiehn, C Plater-Zyberk, CQ Chu, D. Saurigny, DL Scott, E. Esfandiari, E. Lloyd, EGE Vries de, EM Krinner, F Behrens, GR Burmester, GR Burmester, GR Burmester, GR Burmester, GS Firestein, IK Campbell, JA Hamilton, JA Hamilton, JA Hamilton, JC Gasson, JD Griffin, JM Alvaro-Gracia, M Hashimoto, ML Hetland, NJ Zvaifler, R. Stoilov, S Garcia, SA Antoniu, T Kitamura, T Takeuchi, T. W. J. Huizinga, T. Wagner, VA Manivel, W Kievit, W Wang, WD Xu   +47 more
core   +3 more sources

Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics

MedComm, Volume 6, Issue 8, August 2025.
Macrophages originate from the yolk sac, fetal liver, and bone marrow, differentiating into two main subtypes: M1‐like (proinflammatory) and M2‐like (anti‐inflammatory). These subtypes exhibit high plasticity, allowing them to transform in response to environmental cues or therapeutic interventions.
Mengyuan Peng, Niannian Li, Hongbo Wang, Yaxu Li, Hui Liu, Yanhua Luo, Bao Lang, Weihang Zhang, Shilong Li, Liujun Tian, Bin Liu   +10 more
wiley   +1 more source

Insuficiencia respiratoria neonatal asociada a mutación en el gen de la proteína C del surfactante [PDF]

, 2005
La insuficiencia respiratoria en el recién nacido a término durante las primeras semanas de vida extrauterina es una situación poco frecuente. Entre sus causas se incluyen las enfermedades difusas del intersticio pulmonar, un grupo heterogéneo de ...
Alava, E. (Enrique) de, Alzina, V. (Valentín), Bastero, P. (P.), Gaboli, M. (M.), Romero-Montero, A. (A.)   +4 more
core   +1 more source