Results 71 to 80 of about 61,025 (285)

Pulmonary alveolar proteinosis: from classification to therapy

Breathe, 2020
Pulmonary alveolar proteinosis (PAP) is a rare respiratory syndrome characterised by the accumulation of surfactant lipoproteins within the alveoli. According to various pathogenetic mechanisms and aetiologies, PAP is classified as primary, secondary or ...
E. Salvaterra, I. Campo
semanticscholar   +1 more source

Pulmonary Alveolar Proteinosis [PDF]

RadioGraphics, 2008
PULMONARY Alveolar Proteinosis (PAP) is a rare idiopathic lung disease characterized by the accumulation of lipoproteinaceous material within the alveoli of the lungs. Since this disease was first described in 1958, fewer than 500 cases have been reported in the medical literature.
Sridhar, I Seetharam Naidu
openaire   +4 more sources

iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice

Stem Cell Reports, 2018
Summary: Induced pluripotent stem cell (iPSC)-derived hematopoietic cells represent a highly attractive source for cell and gene therapy. Given the longevity, plasticity, and self-renewal potential of distinct macrophage subpopulations, iPSC-derived ...
Adele Mucci, Elena Lopez-Rodriguez, Miriam Hetzel, Serena Liu, Takuji Suzuki, Christine Happle, Mania Ackermann, Henning Kempf, Roman Hillje, Jessica Kunkiel, Ewa Janosz, Sebastian Brennig, Silke Glage, Jens P. Bankstahl, Sabine Dettmer, Thomas Rodt, Gudrun Gohring, Bruce Trapnell, Gesine Hansen, Cole Trapnell, Lars Knudsen, Nico Lachmann, Thomas Moritz   +22 more
doaj   +1 more source

Idiopathic desquamative interstitial pneumonia in a child: a case report. [PDF]

, 2014
Desquamative interstitial pneumonia is a rare form of interstitial lung disease in children. Respiratory symptoms appear progressively, are often subtle, and diagnosis is often delayed by a mean of 6 months after onset.
Aubert, J.D., Bressieux-Degueldre, S., Hafen, G., Rochat, I., Rotman, S.   +4 more
core   +1 more source

Unusual cause of dyspnea in patient with Myelofibrosis: The Ruxolitinib lung

Respiratory Medicine Case Reports
Although pulmonary complications are frequent in patients suffering from hematological diseases, secondary pulmonary alveolar proteinosis is a very rare complication of myelofibrosis.
Antoine El Kik, Maarten Vander Kuylen, Benjamin Bailly, Jennifer Fallas, Benjamin Bondue   +4 more
doaj   +1 more source

Atypical alveolar proteinosis

Indian Journal of Radiology and Imaging, 2018
Alveolar proteinosis is a rare pulmonary disease characterized by intra-alveolar accumulation of surfactant composed of lipoproteinaceous material, related to a lack of surfactant resorption by alveolar macrophages. Crazy paving pattern is characteristic,
Lova Hasina Rajaonarison Ny Ony Narindra, Emmylou Gabrielle Andrianah, Volahasina Francine Ranaivomanana, Christian Tomboravo, Hasina Dina Ranoharison, Jean Noel Bruneton, Ahmad Ahmad   +6 more
doaj   +1 more source

Whole lung lavage combined with Granulocyte-macrophage colony stimulating factor inhalation for an adult case of refractory pulmonary alveolar proteinosis [PDF]

, 2014
BACKGROUND: Whole-lung lavage (WLL) is classically the first-line treatment for symptomatic pulmonary alveolar proteinosis (PAP). However, some patients require multiple WLLs because of refractory nature of their PAP. In this instance, these patients may
Hong yan Yu, Hui Huang, Xue feng Sun, Yan xun Wang, Zuo jun Xu   +4 more
core   +2 more sources

Rapid Serological Detection of Anti‐GM‐CSF Autoantibodies in Autoimmune Pulmonary Alveolar Proteinosis Using a Novel Immunochromatographic Test

Respirology, EarlyView.
We developed a novel ICT with high clinical performance that can distinguish APAP patients from those with other pulmonary diseases. The rapid and simple detection of GMAbs in serum provided a new practical method for the diagnosis of APAP. ABSTRACT Background and Objectives Anti‐GM‐CSF autoantibodies (GMAbs) are essential biomarkers for diagnosing ...
Chika Narita, Kenjiro Shima, Jun‐ichiro Sekiguchi, Yasuyuki Ozeki, Makoto Akiwa, Shohei Koike, Sachiko Yuki, Keiichi Akasaka, Toshiaki Kikuchi, Nobutaka Kitamura, Koh Nakata   +10 more
wiley   +1 more source

Macrophages and lipid metabolism [PDF]

, 2018
Distinct macrophage populations throughout the body display highly heterogeneous transcriptional and epigenetic programs. Recent research has highlighted that these profiles enable the different macrophage populations to perform distinct functions as ...
Remmerie, Anneleen, Scott, Charlotte
core   +1 more source

Long‐term outcome after allogeneic stem cell transplantation for GATA2 deficiency: An analysis of 67 adults and children from France and Belgium

British Journal of Haematology, EarlyView.
The overall survival of patients receiving an allogeneic haematopoietic stem cell transplant (HSCT) for GATA2 deficiency was significantly better if they were transplanted recently, with a bone marrow or cord blood graft and if the transplant was performed before the onset of excess blast. Excess blast before HSCT was the only factor associated with an
Flore Sicre de Fontbrune, Florian Chevillon, Mony Fahd, Kristell Desseaux, Xavier Poiré, Edouard Forcade, Arthur Sterin, Bénédicte Neven, Virginie Gandemer, Sylvain Thepot, Alice Garnier, Bruno Lioure, Ambroise Marcais, Stephanie Nguyen‐Quoc, Suzanne Tavitian, Laure Vincent, Jean Donadieu, Matthieu Resche Riggon, Sylvie Chevret, Marlene Pasquet, Regis Peffault de Latour   +20 more
wiley   +1 more source