Results 81 to 90 of about 8,530 (199)

Lung Lavage Cell Profiles in Diffuse Lung Disease [PDF]

, 2010
The standard armamentarium of tests that are used by pulmonologist are laboratory tests, pulmonary function tests, different radiological techniques (conventional chest-X rays, HRCT scans, etc) and pathohistological analyses of biopsies.
Silvana Smojver-Ježek, Tatjana Peroš-Golubičić   +1 more
core   +1 more source

Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework [PDF]

, 2017
Background The accumulation of MWCNTs in the lung environment leads to inflammation and the development of disease similar to pulmonary fibrosis in rodents.
Banville, Allyson, Goodwin, Laura Rose, Halappanavar, Sabina, Nikota, Jake, Vogel, Ulla Birgitte, Wallin, Hakan, Williams, Andrew, Wu, Dongmei, Yauk, Carole Lynn   +8 more
core   +1 more source

Effective hematopoietic stem cell-based gene therapy in a murine model of hereditary pulmonary alveolar proteinosis

Haematologica, 2020
Hereditary pulmonary alveolar proteinosis due to GM-CSF receptor deficiency (herPAP) constitutes a life-threatening lung disease characterized by alveolar deposition of surfactant protein secondary to defective alveolar macrophage function.
Miriam Hetzel, Elena Lopez-Rodriguez, Adele Mucci, Ariane Hai Ha Nguyen, Takuji Suzuki, Kenjiro Shima, Theresa Buchegger, Sabine Dettmer, Thomas Rodt, Jens P. Bankstahl, Punam Malik, Lars Knudsen, Axel Schambach, Gesine Hansen, Bruce C. Trapnell, Nico Lachmann, Thomas Moritz   +16 more
doaj   +1 more source

Insuficiencia respiratoria neonatal asociada a mutación en el gen de la proteína C del surfactante [PDF]

, 2005
La insuficiencia respiratoria en el recién nacido a término durante las primeras semanas de vida extrauterina es una situación poco frecuente. Entre sus causas se incluyen las enfermedades difusas del intersticio pulmonar, un grupo heterogéneo de ...
Alava, E. (Enrique) de, Alzina, V. (Valentín), Bastero, P. (P.), Gaboli, M. (M.), Romero-Montero, A. (A.)   +4 more
core   +1 more source

Epithelial–Mesenchymal Transition in Human Alveolar Cells Exposed to Indium Chloride

Journal of Applied Toxicology, Volume 45, Issue 11, Page 2353-2362, November 2025.
ABSTRACT For workers in the industry, occupational exposure to indium compounds induces pulmonary disorders, such as interstitial pneumonia. Moreover, lung cancer has been reported in both humans and rodents exposed to indium compounds by inhalation. However, the biological mechanism underlying indium‐induced disorders is poorly understood.
Eiki Kimura, Sharif Ahmed, Haijiao Chen, Yusuke Hiraku   +3 more
wiley   +1 more source

Gravidez de termo em doente com proteinose alveolar e insuficiência respiratória grave

Revista Portuguesa de Pneumologia, 2011
Resumo: A proteinose alveolar pulmonar (PAP) é uma doença rara caracterizada pela acumulação anormal de material lipoproteináceo nos alvéolos, que pode levar a insuficiência respiratória, estando associada a um risco elevado de infecções.
I. Belchior, A.S. Cerdeira, M. Santos, J. Sousa Braga, I. Aragão, A. Martins   +5 more
doaj   +1 more source

Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis [PDF]

, 2015
Pneumonia is a major cause of mortality worldwide and a serious problem in critical care medicine, but the immunophysiological processes that confer either protection or morbidity are not completely understood. We show that in response to lung infection,
Ali, Muhammad, Chen, John W., Chousterman, Benjamin G., Gerhardt, Louisa M.S., Hilgendorf, Ingo, Iwamoto, Yoshiko, Nahrendorf, Matthias, Quach, Tam D., Robbins, Clinton S., Rothstein, Thomas L., Swirski, Filip K., Theurl, Igor, Weber, Georg F., Weissleder, Ralph   +13 more
core   +1 more source

Early IL‐1 Inhibition in Still's Disease: A Window of Opportunity for Improving Outcomes

ACR Open Rheumatology, Volume 7, Issue 10, October 2025.
Objective Still's disease is a complex, multisystemic disorder requiring prompt diagnosis and treatment. This study provides a general assessment of a Still's disease cohort aiming to evaluate the efficacy of early intervention with interleukin‐1 inhibitors (IL‐1i) in achieving clinical inactive disease (CID) and reducing glucocorticoid use in patients
Sara Bindoli, Cristina Cadore, Irina Guidea, Andrea Doria, Roberta Ramonda, Paolo Sfriso   +5 more
wiley   +1 more source

Autoimmune pulmonary alveolar proteinosis prior to myelodysplastic syndrome

Respirology Case Reports, 2020
We report the first case of autoimmune pulmonary alveolar proteinosis (PAP) associated with and preceding myelodysplastic syndrome. A 74‐year‐old female with a history of polymyalgia rheumatica presented with six months history of progressive exertional ...
Chuan Tai Foo, Louis Chhor, Francis Thien   +2 more
doaj   +1 more source

Phase 1b randomized, double-blind study of namilumab, an anti-granulocyte macrophage colony-stimulating factor monoclonal antibody, in mild-to-moderate rheumatoid arthritis [PDF]

, 2017
Change from baseline in swollen (a) and tender (b) joint counts. *Error bars show upper SE for placebo and lower SE for namilumab. SE standard error, SJC swollen joint count, TJC tender joint count.
A. Batalov, AD Cook, AD Cook, AD Cook, AE Nieuwenhuijze van, AJ Fleetwood, AK Ulfgren, AM Gestel van, B. Souberbielle, BC Trapnell, BC Trapnell, BP Hazenberg, C Fiehn, C Plater-Zyberk, CQ Chu, D. Saurigny, DL Scott, E. Esfandiari, E. Lloyd, EGE Vries de, EM Krinner, F Behrens, GR Burmester, GR Burmester, GR Burmester, GR Burmester, GS Firestein, IK Campbell, JA Hamilton, JA Hamilton, JA Hamilton, JC Gasson, JD Griffin, JM Alvaro-Gracia, M Hashimoto, ML Hetland, NJ Zvaifler, R. Stoilov, S Garcia, SA Antoniu, T Kitamura, T Takeuchi, T. W. J. Huizinga, T. Wagner, VA Manivel, W Kievit, W Wang, WD Xu   +47 more
core   +3 more sources