Results 101 to 110 of about 2,645,233 (222)
Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy
Advanced Therapeutics, EarlyView.Tuberculosis (TB) remains a global health challenge, with drug‐resistant strains exacerbating the issue. Metallic nanoparticles (MNPs) show promise in TB diagnosis as sensor probes and in combination therapy with antimycobacterial drugs, requiring further pre‐clinical and clinical research for clinical translation.
Christianah Aarinola Akinnawo +1 more
wiley +1 more source
Advanced Theory and Simulations, EarlyView.Binding energy and electronic structure calculations are used to assess the ability of metal–organic framework (MOF)‐TiO2 composite materials to detect volatile organic compounds found in human breath. Electronic structure changes are measured by comparing density of states profiles using Wasserstein distances.
Maryam Nurhuda +3 more
wiley +1 more source
Bruton tyrosine kinase inhibitors in the management of Waldenström macroglobulinemia
American Journal of Hematology, Volume 98, Issue 2, Page 338-347, February 2023., 2023 Abstract Bruton tyrosine kinase (BTK) inhibitors have taken a central role in the management of patients with Waldenström macroglobulinemia and are the only agents approved by the Food and Drug Administration (FDA) to treat these patients. Although associated with high rates of durable responses, unmet needs with BTK inhibitor therapy include ...
Jorge J. Castillo +4 more
wiley +1 more source
Inhalable Hsa‐miR‐30a‐3p Liposomes Attenuate Pulmonary Fibrosis
Advanced Science, EarlyView.The study explores inhalable hsa‐miR‐30a‐3p‐loaded liposomes as a treatment for bleomycin‐induced pulmonary fibrosis in mice. Hsa‐miR‐30a‐3p is electroporated into liposomes and formulated into a dry powder for inhalation. Delivered via dry powder inhalation, it improves pulmonary function, promotes myofibroblast de‐differentiation by targeting CNPY2 ...
Shuo Liu +14 more
wiley +1 more source
Transmission factors and exposure to infections at work and invasive pneumococcal disease
American Journal of Industrial Medicine, Volume 66, Issue 1, Page 65-74, January 2023., 2023 Abstract Background Working in close contacts with coworkers or the general public may be associated with transmission of invasive pneumococcal disease (IPD). We investigated whether crowded workplaces, sharing surfaces, and exposure to infections were factors associated with IPD.
Kjell Torén +4 more
wiley +1 more source
BMC Pulmonary Medicine, 2018 Background Chronic obstructive pulmonary disease (COPD) is one of the most common comorbidities in community acquired pneumonia (CAP) patients. We aimed to investigate the characteristics and mortality risk factors of COPD patients hospitalized with CAP.
Ruo-Xuan Dai +7 more
doaj +1 more source
Inferring COPD Severity from Tidal Breathing [PDF]
arXiv, 2020 Objective: To develop an algorithm that can infer the severity level of a COPD patient's airflow limitation from tidal breathing data that is collected by a wearable device. Methods: Data was collected from 25 single visit adult volunteers with a confirmed or suspected diagnosis of chronic obstructive pulmonary disease (COPD).
arxiv
Advanced Science, EarlyView.A ROS‐driven in situ oxygen supply nanoventilator based on enzyme nanocapsule can convert ROS into O2 through enzyme cascade reaction between SOD and CAT to relieve lung hypoxia, and kill MRSA by releasing vancomycin, which effectively reduces HIF‐1α expression and balances pro‐inflammatory/anti‐inflammatory macrophages ratio, thereby reducing the ...
Zheng Luo +7 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 37-51, January 2023., 2023 Abstract Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder (HCTD) characterized by arterial dissection/aneurysm/rupture, sigmoid colon rupture, or uterine rupture. Diagnosis is confirmed by detecting heterozygous variants in COL3A1.
Tomomi Yamaguchi +25 more
wiley +1 more source
T‐Cell‐Dependent Bispecific IgGs Protect Aged Mice From Lethal SARS‐CoV‐2 Infection
Advanced Science, EarlyView.This study describes the development of spike‐targeting T‐cell‐dependent bispecific full‐length human immunoglobulin Gs with enhanced efficacy in the treatment of COVID‐19. The significance of T‐cell‐based immunity during infection is highlighted. These results have significant implications for better clinical effectiveness of therapies for COVID‐19 ...
Wenyan Fu +8 more
wiley +1 more source