Results 191 to 200 of about 674,092 (373)

Chronic obstructive pulmonary disease: realities top respiratory medicine problems with the present positions

, 2018
L.D. Todoriko, V.I. Petrenko, О.С. Шевченко, Ihor Semianiv, Anna Boyko   +4 more
openalex   +1 more source

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

Advanced Science, EarlyView.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen, Zhenzhen Wang, Liqiang Song, Qianqian Chen, Hang Zhang, Tao Pan, Jianli Pan, Sheng Zhao, Ting Shang, Hong'en Xu, Xing Lv, Jing Li, Fei Kang, Yongzhan Nie, Feng Zhao, Lei Shi, Zheng Wang   +16 more
wiley   +1 more source

Prevalence of obstructive airway disease in pulmonary function tests of patients visiting respiratory medicine out patient department

, 2023
S. Thritia, Hafis Deshmukh, Ashish A. Deshmukh, S.E. Jadhav, Shivprasad Kasat, Arya Mariam Roy, S. Thamil Mani   +6 more
openalex   +2 more sources

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

Pulmonary‐Targeted Nanoparticles Interrupt the Malignant Mechanical and Biochemical Signaling Crosstalk for Idiopathic Pulmonary Fibrosis Therapy

Advanced Science, EarlyView.
Idiopathic pulmonary fibrosis (IPF) progression is driven by TGF‐β induced biochemical signals and mechanical signals from increased ECM stiffness. Pulmonary‐targeted VB‐RT NPs not only eliminate excessive ROS and penetrate the dense ECM collagen barrier via NO release, but also simultaneously interrupt the persistent malignant between mechanical and ...
Xue‐Na Li, Ya‐Ping Lin, Xi‐Xi Ma, Yue‐Fei Fang, Hui Wang, Chun‐Hui Cui, Chen Zhang, Jin‐You Piao, Jee‐Heon Jeong, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +11 more
wiley   +1 more source

Derivation and validation of a clinical model to identify cryptococcosis from suspected malignant pulmonary nodules: A dual‐center case‐control study

Clinical and Translational Medicine, 2021
Bei Mao, Hai Zhang, Wen‐Wen Wang, Hai‐Wen Lu, Jia‐Wei Yang, Sen Jiang, Xiao‐Dan Ye, Feng Li, Jin‐Fu Xu   +8 more
doaj   +1 more source

Prevalence of Hypertension in Patients with Chronic Obstructive Pulmonary Disease Attending Respiratory Medicine OPD

, 2017
Dr Rohit Singh
openalex   +1 more source

Arts for health: SingingMetteKaasgaardPostDoc, PhD, MSc, Classical singer and singing pedagogue, Institute of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, and Pulmonary Research Unit, Department of Respiratory Medicine, Zealand University Hospital Roskilde and Naestved, Denmark.mkaasgaard@health.sdu.dk

, 2022
J. Yoon Irons, Grenville Hancox
openalex   +1 more source

Interior Decorative VOCs Elevate T Cell‐Mediated Obstructive Lung Disease Risks via Osteogenesis‐Driven Lymphoid‐Biased Hematopoiesis

Advanced Science, EarlyView.
This study utilizes a whole‐body inhalation model to reveal that interior decorative VOCs exposure persistently elevates alveolar T cells. This increase is attributed to lymphoid‐biased hematopoiesis in the bone marrow, which is further driven by IL‐6/IL‐17A‐mediated osteogenic differentiation.
Hongyan Yu, Jingxu Zhang, Qingping Liu, Duxing Li, Ruonan Pan, Gan Miao, Yidi Chen, Zhe Kou, Guangbo Qu, Rong Zhang, Xiaoting Jin, Yuxin Zheng   +11 more
wiley   +1 more source

Neurogenic Pulmonary Edema Following Acute Subarachnoid Hemorrhage: A Case Report and Review of Emergency Management. [PDF]

J Acute Med
Woon WK, Tanapima V, Tsai HL.
europepmc   +1 more source