Results 221 to 230 of about 659,780 (372)

Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection

open access: yesAdvanced Science, EarlyView.
Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi   +4 more
wiley   +1 more source

Quantitative Imaging Markers on HRCT Predict Rapid Progression and Adverse Events of Patients with Idiopathic Inflammatory Myopathies-Related Interstitial Lung Disease

open access: yesInternational Journal of General Medicine
Hongyi Wang,1,2,* Yuhui Qiang,2– 4,* Jianping Wang,3,5 Yifei Ni,1,5 Anqi Liu,1,5 Jie Du,1,5 Yanhong Ren,2 Shiyao Wang,2 Jing Geng,2 Bingbing Xie,2 Min Liu,5 Huaping Dai2 1China-Japan Friendship Hospital (Institute of Clinical Medical ...
Wang H   +11 more
doaj  

Mechanotransduction in Shaping Immunity: Pathways, Crosstalk, and Pathophysiological Relevance

open access: yesAdvanced Science, EarlyView.
This review comprehensively summarizes the role of mechanotransduction in shaping immunity. It details how immune cells respond to biomechanical cues via mechanotransduction cascades and emphasizes the mechanical crosstalks within the immune microenvironment. The emerging significance of mechanoimmunology in both health and diseases is also highlighted.
Ruijiao Yan   +7 more
wiley   +1 more source

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo   +9 more
wiley   +1 more source

The microbiome in respiratory medicine: current challenges and future perspectives

open access: yesEuropean Respiratory Journal, 2017
R. Faner   +13 more
semanticscholar   +1 more source

High Altitude Pulmonary Edema [PDF]

open access: yes, 2020
Charnigo, Aubri, Yee, Jennifer
core  

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