Results 271 to 280 of about 626,135 (375)

Lung‐Penetrating Biomimetic Extracellular Vesicle Spherical Nucleic Acids for Pulmonary Fibrosis Therapy Through ROS Scavenging and Anti‐Inflammatory Effects

Aggregate, EarlyView.
This work describes a biomimetic extracellular vesicle‐spherical nucleic acid (BEV‐SNA) platform for idiopathic pulmonary fibrosis (IPF) therapy. BEV‐SNA is composed of mechanically extruded BEVs from primary MSCs and cholesterol‐modified ssDNA that are assembled through hydrophobic interactions.
Saiyun Lou, Jiangpo Ma, Pan Fu, Lin Li, Jingyun Huang, Fangxue Jing, Yuhui Wang, Sihua Qian, Jianping Zheng, Jiang Li, Zhaoxing Dong, Kaizhe Wang   +11 more
wiley   +1 more source

A rare cause of acute upper airway obstruction: a case report. [PDF]

Int J Emerg Med
Harding J, Dioszeghy C.
europepmc   +1 more source

Conjugated Polymer Composite Flexible Wood Hydrogel‐Mediated Sequential NIR‐II Photothermal and Photodynamic Anti‐Bacteria and Macrophage Polarization for Acute Sinusitis

Aggregate, EarlyView.
This study developed a D–A–D–A conjugated polymer with NIR‐II absorption for phototherapy. The conjugated polymer nanoparticles were functionalized with hemin and embedded in a wood‐based hydrogel (LM@P/S@CP@Hemin). In MRSA‐infected rabbit sinusitis models, the NIR‐II laser treatment showed outstanding antibacterial effect, reduced inflammation, and ...
Lei He, Xiaofeng Ma, Yongze Liu, Genyuan Li, Juqing Cui, Jun Zhang, Yuanyuan Li, Ben Zhong Tang, Wentao Wang   +8 more
wiley   +1 more source

Microbial profiling of community-acquired pneumonia in patients with and without chronic obstructive pulmonary disease: a comprehensive molecular diagnostics study. [PDF]

Pneumonia (Nathan)
Markussen DL, Lindemann C, Serigstad S, Jenum S, Ritz C, Grewal HMS.   +5 more
europepmc   +1 more source

Classification of Pulmonary Nodules Using Multimodal Feature‐Driven Graph Convolutional Networks with Specificity Proficiency

Advanced Intelligent Systems, EarlyView.
The radiomics feature could save the storage space of all medical samples; on the other hand, it avoids data leakage. Graph convolutional neural networks could summarize the similarity of benign and malignant pulmonary nodules to improve the performance in distinguishing them with radiomics and common clinical features.
Renjie Xu, Zhanlue Liang, Dan Wang, Rui Zhang, Jiayi Li, Lingfeng Bi, Kai Zhang, Weimin Li   +7 more
wiley   +1 more source

Role of home-based pulmonary rehabilitation programs for disease progression and quality of life in patients with stable bronchiectasis: a single-center RCT. [PDF]

Front Med (Lausanne)
Min S, Liu H, Zhang Y, Wang J, Wang L, Jiang Y, Shi S.   +6 more
europepmc   +1 more source

AI‐Driven Microphysiological Systems for Advancing Nanoparticle Therapeutics

Advanced Intelligent Systems, EarlyView.
This review outlines recent advances in integrating artificial intelligence with microphysiological systems for nanoparticle evaluation. It highlights data‐driven optimization, image‐based prediction, and AI‐enabled analysis frameworks that advance translational research and support the development of personalized nanomedicine. Nanoparticles (NPs) play
Yedam Lee, Jaehong Min, Sujin Kim, Jihoon Ko   +3 more
wiley   +1 more source

Development of a Scoring System to Predict Suboptimal Peak Inspiratory Flow in Patients With Chronic Obstructive Pulmonary Disease. [PDF]

J Korean Med Sci
Kim SH, Kim Y, Rhee CK, Lee H, Lee CY, Park JH, Ra SW, Park YB, Yoo KH, Kim HJ.   +9 more
europepmc   +1 more source

R‐APEX: A Knowledge Graph–Based Platform for the Elucidation of the Toxicological Mechanisms of Ambient Particulate Matter

Advanced Intelligent Systems, EarlyView.
R‐APEX is a knowledge graph platform developed to investigate how air pollutants such as particularly fine particulate matter (PM2.5) affect human health. By integrating large‐scale biomedical data and using machine learning, it reveals pollutant–gene–disease associations.
Zhixing Zhu, Jingcheng Yang, Xiaofei Li, Zhijie Zheng, Georgi Z. Genchev, Yuchen Ye, Liang Liu, Zihan Ran   +7 more
wiley   +1 more source

Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas

Advanced Intelligent Systems, EarlyView.
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang, Dingsi Xiang, Shengli Mi, Jiajun Huang   +3 more
wiley   +1 more source