Results 131 to 140 of about 423,899 (348)

Inhaled nitric oxide for high-altitude pulmonary edema [PDF]

, 1996
BACKGROUND. Pulmonary hypertension is a hallmark of high-altitude pulmonary edema and may contribute to its pathogenesis. When administered by inhalation, nitric oxide, an endothelium-derived relaxing factor, attenuates the pulmonary vasoconstriction ...
Ballmer, P. E., Bartsch, P., Delabays, A., Eichenberger, U., Fikrle, A., Kleger, G. R., Nicod, P., Savcic, M., Scherrer, U., Vollenweider, L.   +9 more
core   +1 more source

Knowledge, Attitude, and Practice on Atrial Fibrillation and Atrial Fibrillation Screening in High‐Risk Population: A Cross‐Sectional Study

AGING MEDICINE, EarlyView.
Distribution of KAP scores for participants ≤ 65 versus > 65 years. ABSTRACT Objectives Atrial fibrillation (AF) is a common clinical arrhythmia. Failure to identify AF leaves patients at a considerably higher risk of disability and death, making its early screening and prevention extremely important. This study aimed to investigate knowledge, attitude,
Zhong Yi, Xinxin Yan, Shaozhi Xi, Lijuan Zhu, Rui Liu, Jing Li, Songwei Ru, Xiu Zheng, Jingxuan Qiu, Chunqi Wang, Na Guo, Yimin Wang, Dayong Gao   +12 more
wiley   +1 more source

Right ventricular-pulmonary arterial coupling and pulmonary hypertension in hemodialysis: insights into structural cardiac changes and clinical implications

Renal Failure
Objectives This cross-sectional analysis from the CZecking Heart Failure in patients with advanced Chronic Kidney Disease trial (ISRCTN18275480) examined pulmonary hypertension and right ventricular-pulmonary arterial coupling in patients on chronic ...
Kristina Buryskova Salajova, Jan Malik, Lucie Kaiserova, Zuzana Hladinova, Zdenka Hruskova, Simona Janakova, Vladimir Tesar, Satu Sinikka Pesickova, Kristyna Michalickova, Katarina Rocinova, Barbora Szonowska, Anna Valerianova   +11 more
doaj   +1 more source

Clinical trial design and new therapies for pulmonary arterial hypertension

European Respiratory Journal, 2019
Until 20 years ago the treatment of pulmonary arterial hypertension (PAH) was based on case reports and small series, and was largely ineffectual. As a deeper understanding of the pathogenesis and pathophysiology of PAH evolved over the subsequent two ...
O. Sitbon, M. Gomberg-Maitland, J. Granton, M. Lewis, S. Mathai, M. Rainisio, N. Stockbridge, M. Wilkins, R. Zamanian, L. Rubin   +9 more
semanticscholar   +1 more source

Association Between Cholecystectomy and Gastric Cancer in a Cohort Study in Taiwan

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Objective The association between cholecystectomy and gastric cancer is undetermined. The objective of this study was to assess whether subjects with cholecystectomy are at risk of gastric cancer in Taiwan. Methods This study used data from a cohort of 2 000 000 beneficiaries over a twelve‐year period (2010–2021) from the Taiwan National ...
Kuan‐Fu Liao, Cheng‐Chan Yu, Sheng‐Chun Chiu, Yu‐Hung Kuo, Shih‐Wei Lai   +4 more
wiley   +1 more source

Osteopontin lung gene expression is a marker of disease severity in pulmonary arterial hypertension

Respirology (Carlton South. Print), 2019
Osteopontin (OPN) is a pleiotropic cytokine involved in the proliferation of pulmonary artery smooth muscle cells (PA‐SMC). OPN is upregulated in the lungs of patients with pulmonary hypertension (PH) associated with pulmonary fibrosis, suggesting that ...
M. Mura, M. Cecchini, Mariamma G. Joseph, J. Granton   +3 more
semanticscholar   +1 more source

Deep Learning Model for Predicting Operative Mortality After Total Gastrectomy: Analysis of the Japanese National Clinical Database (NCD)

Annals of Gastroenterological Surgery, EarlyView.
Deep learning‐based prediction model for operative mortality using the National Clinical Database (NCD). The model achieved a C‐statistic of 0.74. ABSTRACT Background Radical gastrectomy with lymph node dissection is the primary treatment for gastric cancer.
Ryosuke Fukuyo, Hiroyuki Yamamoto, Masanori Tokunaga, Yusuke Kinugasa, Yoshihiro Kakeji, Ken Shirabe   +5 more
wiley   +1 more source

Effect of pulmonary hypertension on outcome of pulmonary tuberculosis

International Journal of Mycobacteriology, 2015
Objectives: Pulmonary hypertension is a serious disorder with catastrophic outcomes. This study aimed to evaluate the effect of pulmonary arterial hypertension on the outcome among new cases of pulmonary tuberculosis.
Majid Marjani, Payam Tabarsi, Parvaneh Baghaei, Afshin Moniri, Majid Malekmohammad   +4 more
doaj  

A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension

European Respiratory Journal, 2018
Pulmonary arterial hypertension (PAH) is a deadly disease with no cure. Alternate conversion of angiotensin II (AngII) to angiotensin-(1–7) (Ang-(1–7)) by angiotensin-converting enzyme 2 (ACE2) resulting in Mas receptor (Mas1) activation improves rodent ...
A. Hemnes, A. Rathinasabapathy, E. Austin, E. Brittain, E. J. Carrier, Xinping Chen, J. Fessel, C. Fike, P. Fong, N. Fortune, Robert E. Gerszten, Jennifer A. Johnson, M. Kaplowitz, J. Newman, R. Piana, M. Pugh, T. Rice, I. Robbins, L. Wheeler, Chang Yu, J. Loyd, J. West   +21 more
semanticscholar   +1 more source

Effect of the sphingosine kinase 1 selective inhibitor, PF-543 on arterial and cardiac remodeling in a hypoxic model of pulmonary arterial hypertension [PDF]

, 2016
Recent studies have demonstrated that the expression of sphingosine kinase 1, the enzyme that catalyses formation of the bioactive lipid, sphingosine 1-phosphate, is increased in lungs from patients with pulmonary arterial hypertension. In addition, Sk1-/
Al Washih, Mohammed, Futerman, Anthony H., Kennedy, Simon, MacRitchie, Neil, Pyne, Nigel J., Pyne, Susan, Volpert, Giora, Watson, David G.   +7 more
core   +1 more source