Results 161 to 170 of about 52,661 (244)
ESC Heart Failure, EarlyView.Abstract Aims Biomarkers are pivotal in the management of heart failure (HF); however, their lack of cardiac specificity could limit clinical utility. This study aimed to investigate the transcoronary changes and intracardiac production of these biomarkers.
Jie Ren +10 more
wiley +1 more source
ESC Heart Failure, EarlyView.Abstract Background Chronic kidney disease (CKD) has a high prevalence in patients with heart failure (HF) and is associated with prolonged hospitalization, increased need for intensive care and mortality. There is an urgent need to identify factors that influence the interaction between heart and kidney disorders, often described as cardiorenal ...
Alexander Reinecke +7 more
wiley +1 more source
Mitral valve transcatheter edge‐to‐edge repair in the elderly—A safe and effective therapy
ESC Heart Failure, EarlyView.Mitral valve transcatheter edge‐to‐edge repair in elderly patients is safe and offers comparable mitral valve regurgitation reduction and symptom relief to younger patients. At 3 years, increased all‐cause mortality is observed in elderly patients with advanced heart failure and elevated EuroSCORE II.
Dominik Felbel +6 more
wiley +1 more source
Inter‐atrial block as a predictor of adverse outcomes in patients with HFpEF
ESC Heart Failure, EarlyView.Abstract Aims Inter‐atrial block (IAB), a marker of electrical atrial dysfunction, is associated with an increased risk of atrial fibrillation (AF) and adverse events in various populations. The prognostic impact of IAB in heart failure (HF) with preserved ejection fraction (HFpEF) remains unknown.
Jerremy Weerts +11 more
wiley +1 more source
ESC Heart Failure, EarlyView.Abstract Aims Wild‐type transthyretin cardiac amyloidosis (ATTRwt) is a cardiomyopathy causing myocardial hypoperfusion and impaired cardiac mitochondrial function. Trimetazidine is an antianginal agent used in patients with stable angina pectoris, which improves cardiac contractility and mitochondrial function.
Bertil Thyrsted Ladefoged +5 more
wiley +1 more source
ESC Heart Failure, EarlyView.Abstract Aims Differences in guideline‐directed medical therapy (GDMT) and clinical outcomes have been observed between heart failure (HF) patients with atrial fibrillation (AF) versus those in sinus rhythm. This study evaluated the effects of up‐titration of HF therapies, consisting of beta‐blockers, angiotensin‐converting‐enzyme inhibitors (ACEis ...
Arietje J.L. Zandijk +6 more
wiley +1 more source
ESC Heart Failure, EarlyView.Abstract Aims This study aimed to conduct a phase 2 proof‐of‐concept and safety study to evaluate the effect of ENIBARCIMAB (EN), a non‐neutralizing humanized monoclonal antibody targeting the N‐terminus of adrenomedullin (ADM), administered immediately after stabilization with standard of care (SoC) treatment, in patients hospitalized for acute heart ...
Anggoro Budi Hartopo +19 more
wiley +1 more source