Results 71 to 80 of about 52,661 (244)

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Pulse dose steroids in severe pulmonary arterial hypertension secondary to systemic lupus erythematosus

SAGE Open Medical Case Reports, 2017
Objective: The pulmonary vascular targeted treatment for systemic lupus erythematosus–associated pulmonary arterial hypertension is similar to other connective tissue disease–associated pulmonary arterial hypertension.
Cody Lee, Jean Elwing
doaj   +1 more source

The relation of Echocardiographic findings to pulmonary Function tests in patients with Chronic obstructive Pulmonary Disease

مجلة كلية الطب, 2009
Background: Chronic obstructive pulmonary disease (COPD) is a common disease and it accounts for over 10% of all hospital medical admission. Cigarette smoking is the most important risk factor.
Kassim M. Sultan, Muataz F. Hussain, Ammar A. Ismael   +2 more
doaj   +1 more source

Robust heartbeat detection using multimodal recordings and ECG quality assessment with signal amplitudes dispersion [PDF]

Khavas ZR, Asl BM. Robust heartbeat detection using multimodal recordings and ECG quality assessment with signal amplitudes dispersion. Computer methods and programs in biomedicine. 2018 Sep 1;163:169-82, 2021
Method: In this study, a new method is introduced for distinguishing noise-free segments of ECG from noisy segments that use sample amplitude dispersion with an adoptive threshold for variance of samples amplitude and a method which uses compatibility of detected beats in ECG and some of the other signals which are related to the heart activity such as
arxiv  

Modern treatment to reduce pulmonary arterial pressure in pulmonary arterial hypertension [PDF]

Journal of Cardiology, 2018
Treatment goals in pulmonary arterial hypertension (PAH) include improved quality of life and exercise capacity as well as improved life prognosis. In our experience, only remarkable reductions in pulmonary arterial pressure (PAP) improve long-term survival. Lowering PAP could contribute to reverse remodeling by reducing hemodynamic stress.
Satoshi Akagi, Hiromi Matsubara, Kazufumi Nakamura, Hiroshi Ito   +3 more
openaire   +3 more sources

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

Advanced Science, EarlyView.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin, Chuling Li, Zhaoyi Wu, Zhenquan Tang, Jingfang Xie, Guoquan Wei, Zhiwen Yang, Senlin Huang, Yijin Chen, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Guojun Chen, Hao Zheng, Jianping Bin   +15 more
wiley   +1 more source

4.9 PROPORTIONAL PRESSURE RELATIONS IN THE PULMONARY ARTERIAL SYSTEM

Artery Research, 2016
Background – Objectives: The pulmonary arterial system can be characterized by: 1.A constant product of Pulmonary Vascular Resistance (PVR) and Total Arterial Compliance (TAC) with Tau=PVRxTAC≈0.7 seconds (1).
Nico Westerhof, Louis Handoko
doaj   +1 more source

Advancements in Bio‐Integrated Flexible Electronics for Hemodynamic Monitoring in Cardiovascular Healthcare

Advanced Science, EarlyView.
This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley   +1 more source

Evaluation of serum uric acid level in systemic lupus erythematosus patients with normal and high pulmonary arterial hypertension

BioMedicine, 2018
Background: Systemic lupus erythematosus (SLE) is a life-threatening multisystem inflammatory condition affected any organ system. Considering the role of uric acid as a pro-inflammatory compound in high pulmonary arterial pressure, serum levels of uric ...
Aghdashi Miramir, Behnemoon Mahsa, Mahmoodi Rad Jila, Rabiepour Masoumeh   +3 more
doaj   +1 more source

Ação da adenosina na circulação pulmonar de pacientes com hipertensão pulmonar primária Effect of adenosine on pulmonary circulation in patients with primary pulmonary hypertension

Jornal Brasileiro de Pneumologia, 2005
INTRODUÇÃO: A adenosina é um nucleosídeo com potente ação vasodilatadora. Apesar de seus efeitos sobre o território arterial pulmonar ser conhecido, seu efeito sobre o território capilar/venoso ainda não foi descrito.
Rogerio Souza, Marcelo Britto Passos Amato, Sergio Eduardo Demarzo, Daniel Deheinzelin, Carmen Silvia Valente Barbas, Pedro Caruso, Carlos Roberto Ribeiro Carvalho   +6 more
doaj   +1 more source