Results 151 to 160 of about 121,472 (372)

Weight Is a Questionable Predictor of Alveolar Membrane Diffusing Capacity and Pulmonary Capillary Blood Volume Even in Moderately Obese Subjects [PDF]

, 2010
Gerald S. Zavorsky
openalex   +1 more source

Nanoparticle‐Modified Nanofibers Induce Ferroptosis and Stimulate Antitumor Immunity for Melanoma Therapy

Advanced Science, EarlyView.
This study presents a nanoparticle‐embedded nanofiber (5F/STFM/R‐ES) to inhibit melanoma growth and reduce the risk of metastasis and recurrence. The drug delivery system induces ferroptosis and potentiates immunotherapy through resiquimod (R848) and Fe/Mn‐based metal‐polyphenol networks (TFM).
Mingyang Li, Rongrong Li, Baotong Xu, Yuhan Lian, Chenyu Yang, Jingwen Li, Junhao Liang, Linhan Ding, Dongsheng Zhang, Jing Guo, Xiao Fu   +10 more
wiley   +1 more source

Referential equations for pulmonary diffusing capacity using GAMLSS models derived from Japanese individuals with near-normal lung function. [PDF]

PLoS One, 2022
Wada Y, Goto N, Kitaguchi Y, Yasuo M, Hanaoka M.   +4 more
europepmc   +1 more source

P2.05-13 Impact of Diffusing Capacity for Postoperative Pulmonary Complications in Patients Without Obstructive Pulmonary Disease [PDF]

, 2019
Sun Hye Shin, J.H. Cho, H.K. Kim, Yong Soo Choi, J. Kim, Jae Ill Zo, Young Mog Shim, H.Y. Park   +7 more
openalex   +1 more source

Tumor‐Derived Interleukin 35 Promotes Fibrosis in the Tumor Microenvironment of Pancreatic Cancer by Activating Pancreatic Stellate Cells

Advanced Science, EarlyView.
This study demonstrates that tumor‐derived IL‐35 promotes pancreatic cancer fibrosis by indirectly activating pancreatic stellate cells through IGFBP2/IGF‐1R/PI3K‐Akt and Tsp‐1/TGF‐β pathways. IL‐35 blockade reduces stromal fibrosis, restores chemosensitivity, and synergizes with gemcitabine‐based regimens, highlighting IL‐35 as a promising therapeutic
Hui Li, Huizhi Sun, Jing Liu, Yan Wu, Lin Wei, Jianming Li, Yudong Yuan, Peng Xie, Chao Xu, Guolu Luo, Yuqi Guan, Yukuan Feng, Antao Chang, Jihui Hao, Chongbiao Huang   +14 more
wiley   +1 more source

Evolving Concepts in Progressive Pulmonary Fibrosis: A Clinical Update

Journal of Respiration
Progressive pulmonary fibrosis (PPF) is a clinical syndrome associated with worsening quality of life and increased mortality among patients with various interstitial lung diseases.
María Belén Noboa-Sevilla, Fernanda Hernández-González, Sandra Cuerpo-Cardeñosa, Xavier Alsina-Restoy, Nancy Pérez-Rodas, Alejandro Frino-García, Miguel Alonso-Villares, Elvis Matheus-Ramírez, Jacobo Sellarés   +8 more
doaj   +1 more source

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

Advanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour, Austin D. Evans, Camilla Karoliina Bergström, Vignesh Kumar Rangasami, Sumanta Samanta, Nithiyanandan Krishnan, Yuji Teramura, Bo Nilsson, Patricia Hedenqvist, Elin Manell, Jons Hilborn, Marianne‐Jensen Waern, Oommen P. Varghese, Pirjo Laakkonen, Oommen P. Oommen   +14 more
wiley   +1 more source

Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patients

Brazilian Journal of Medical and Biological Research, 2007
The objective of the present study was to determine if there is a health-related quality of life (HRQL) instrument, generic or specific, that better represents functional capacity dysfunction in idiopathic pulmonary fibrosis (IPF) patients.
C.S. Zimmermann, C.R.F. Carvalho, K.R. Silveira, W.P.S. Yamaguti, E.V. Moderno, J.M. Salge, R.A. Kairalla, C.R.R. Carvalho   +7 more
doaj  

DCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex

Advanced Science, EarlyView.
This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.
Zhenyi Wang, Huanhuan Huang, Kaizong Huang, Xiaowen Cui, Leilei Wu, Renyu Lin, Zhe Zhao, Hua Chen, Cheng Zheng, Weilin Jin, Song Chen, Jiayan Chen, Yaping Xu, Dongping Wei   +13 more
wiley   +1 more source

Burn‐Safe Biodegradable Magnetocaloric Composites for Temperature‐Controlled Biomedical Applications

Advanced Science, EarlyView.
This work investigates a magnetocaloric (Mn,Fe)2(P,Si) compound tailored for precise, self‐regulating heating in biomedical use. With a Curie temperature tuned at 43 °C, it enables therapeutic activation without overheating. Encapsulation in a composite ensures controlled temperature rise under an alternating magnetic field (AMF), with high ...
Pornpawee Uliss, Wuliji Hanggai, Friso Kahler, Elena Aprea, Qi Jia, Vasiliki Gkouzioti, Jean‐Philippe Frimat, Ekkes Brück, Clementine M. Boutry   +8 more
wiley   +1 more source