Background With the development and market launch of several new domestic lung diffusing capacity testing instruments, the clinical reliability of the MeHow MeAir 9000 spirometer, featuring a novel turning valve structure, needs to be validated ...
Shihua Yao+13 more
doaj +1 more source
Increased levels of hyaluronic acid in bronchoalveolar lavage from patients with interstitial lung diseases, relationship with lung function and inflammatory cells recruitment [PDF]
Purpose: Interstitial Lung Diseases (ILD) are characterized by inflammation and fibrosis. It described the role of hyaluronic acid (HA) as an immune-regulator. It is not known if HA contributes to the recruitment of inflammatory cells associated with ILD.
Auteri, Santiago+6 more
core +1 more source
Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer
This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang+16 more
wiley +1 more source
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran+7 more
wiley +1 more source
Treatment of Advanced Emphysema with Emphysematous Lung Sealant (AeriSeal (R)) [PDF]
Background: This report summarizes initial tests of an emphysematous lung synthetic polymer sealant (ELS) designed to reduce lung volume in patients with advanced emphysema.
A. Ernst+16 more
core +1 more source
The measurement of the pulmonary diffusing capacity in the presence of lung disease.
Recent work (1-4) has shown that the rate of pulmonary gas diffusion is abnormal in a variety of clinical conditions, and its measurement seems certain to become a necessary part of any complete evaluation of pulmonary function.
BY D. V. Bates
semanticscholar +1 more source
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang+10 more
wiley +1 more source
Incidence and affecting factors of pulmonary diffusing capacity impairment with COVID-19 survivors 18 months after discharge in Wuhan, China. [PDF]
Xu B+8 more
europepmc +2 more sources
STUDIES OF RESPIRATORY PHYSIOLOGY IN CHILDREN. VI. LUNG DIFFUSING CAPACITY, DIFFUSING CAPACITY OF THE PULMONARY MEMBRANE AND PULMONARY CAPILLARY BLOOD VOLUME IN CONGENITAL HEART DISEASE* [PDF]
Giovanni Bucci, Charles D. Cook
openalex +1 more source
The effect of aging and cardiorespiratory fitness on the lung diffusing capacity response to exercise in healthy humans [PDF]
Aging is associated with deterioration in the structure and function of the pulmonary circulation. We characterized the lung diffusing capacity for carbon monoxide (DLCO), alveolar-capillary membrane conductance (Dm(CO)), and pulmonary-capillary blood ...
Alex R. Carlson+7 more
core +1 more source