Results 261 to 270 of about 30,235 (338)

Pulmonary function prediction in lung cancer resection candidates: the latest insights. [PDF]

Breathe (Sheff)
Orlandi R, Degiovanni S, Uslenghi C, Anghinelli A, Besana P, Palleschi A.   +5 more
europepmc   +1 more source

Finerenone, chronic obstructive pulmonary disease, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS‐HF trial

European Journal of Heart Failure, EarlyView.
The beneficial effects of finerenone in patients with heart failure (HF) and mildly reduced or preserved ejection fraction were consistent, regardless of a history of chronic obstructive pulmonary disease (COPD) status. BMI, body mass index; LVEF, left ventricular ejection fraction; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide.
Jawad H. Butt, Pardeep S. Jhund, Alasdair D. Henderson, Brian L. Claggett, Akshay S. Desai, Carolyn S.P. Lam, Katharina Mueller, Markus F. Scheerer, Prabhakar Viswanathan, Michele Senni, Sanjiv J. Shah, Adriaan A. Voors, Faiez Zannad, Bertram Pitt, Muthiah Vaduganathan, Scott D. Solomon, John J.V. McMurray   +16 more
wiley   +1 more source

The Cross-Sectional Area of Erector Spinae Muscles Obtained from Chest CT Is an Independent Predictor of Death in COPD. [PDF]

Int J Chron Obstruct Pulmon Dis
Liu J, Li R, Li Y, Ge S, Yao S, Zhang R, Fu H, Ning P, Zhang J, Zhang M.   +9 more
europepmc   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

Exploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang, Shuihao Zhao, Haijie Zhao, Mingzhang Wen, Zhong Guo   +4 more
wiley   +1 more source

Quantitative Assessment of High-resolution Computer Tomography Imaging in a Super-responder to Nintedanib Therapy in a Patient with Idiopathic Pulmonary Fibrosis. [PDF]

Intern Med
Itano J, Ishiga M, Fujii M, Takemoto M, Hayashibara N, Kimura G, Tanimoto Y.   +6 more
europepmc   +1 more source

RE: Comment on: Pulmonary Function and Diffusing Capacity of Carbon Monoxide in Hypersensitivity Pneumonitis: An Observational Study of 152 Patients

Sonam Spalgais, Parul Mrigpuri, N Ravishankar, Raj Kumar   +3 more
openalex   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Lung structure and function, post-treatment, in strictly defined subclinical pulmonary tuberculosis: a prospective cohort study in Canada. [PDF]

ERJ Open Res
Long R, Collins S, Stickland MK, Kirby M, Lau A, Barrie J, Winter C, Armstrong G, Wong E, Parhar A, Yehya J, Bourbeau J, Tan WC, Doroshenko A.   +13 more
europepmc   +1 more source

The Nutritional and Bioactive Components, Potential Health Function and Comprehensive Utilization of Hawthorn: A Review

Food Frontiers, EarlyView.
This review systematically and comprehensively analyzes hawthorn (Crataegus spp.), covering its bioactive constituents, properties, and processed products. ABSTRACT Hawthorn is widely cultivated in China, with excellent varieties and steadily increasing production.
Wenteng Yang, Quanhong Gao, Kun Ran, Mingyue Jiao, Xiaodan Fu, Zhenlin Han, Chao Liu, Ningyang Li   +7 more
wiley   +1 more source