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Increased risk of acute exacerbation in obstructive airway disease: the impact of metabolic dysfunction-associated steatotic liver disease and small airway dysfunction. [PDF]
Tseng CH +12 more
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Erratum: Airway Mucus Plugs on Chest Computed Tomography Are Associated with Exacerbations in Chronic Obstructive Pulmonary Disease. [PDF]
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Erratum: Towards Precision Treatment of Chronic Obstructive Pulmonary Disease Exacerbations: The Role of Specialized Proresolving Mediators. [PDF]
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Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and progressive airflow obstruction. Tobacco smoking is the leading cause but not the only one.
W. Labaki, Sharon R. Rosenberg
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Chronic obstructive pulmonary disease
Chronic Obstructive Pulmonary Disease (COPD) is related to smoking as the main etiological agent although there are other risk factors that can interact influencing the development of the disease. The definition of COPD is based on three points: the presence of persistent respiratory symptoms, exposure to risk agents, and a non-reversible obstructive ...
S. Christenson +3 more
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Chronic Obstructive Pulmonary Disease
Comprehensive Physiology, 2014AbstractCOPD is characterized by airflow limitation that is not fully reversible. The morphological basis for airflow obstruction results from a varying combination of obstructive changes in peripheral conducting airways and destructive changes in respiratory bronchioles, alveolar ducts, and alveoli. A reduction of vascularity within the alveolar septa
BRUSASCO, VITO, Martinez, Fernando
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Chronic obstructive pulmonary disease
Nature Reviews Disease Primers, 2015Chronic obstructive pulmonary disease (COPD) is a common disease with high global morbidity and mortality. COPD is characterized by poorly reversible airway obstruction, which is confirmed by spirometry, and includes obstruction of the small airways (chronic obstructive bronchiolitis) and emphysema, which lead to air trapping and shortness of breath in
Peter J, Barnes +6 more
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Chronic obstructive pulmonary disease
The Lancet, 2017Chronic obstructive pulmonary disease (COPD) kills more than 3 million people worldwide every year. Despite progress in the treatment of symptoms and prevention of acute exacerbations, few advances have been made to ameliorate disease progression or affect mortality.
Klaus F, Rabe, Henrik, Watz
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