Results 51 to 60 of about 269,597 (228)

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng   +12 more
wiley   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im   +10 more
wiley   +1 more source

Biodegradable, Humidity‐Insensitive Mask‐Integrated E‐Nose for Sustainable and Non‐Invasive Continuous Breath Analysis

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a paper‐based biodegradable, humidity‐insensitive e‐nose for real‐time breath analysis, addressing challenges in existing technologies such as humidity interference, high costs, and environmental impact. Featuring hydrophobic polymer coatings, these sensors reliably detect VOCs even in high‐moisture environments.
Indrajit Mondal   +2 more
wiley   +1 more source

Background of the development of the concept of physical rehabilitation of patients with COPD

open access: yesJournal of Education, Health and Sport, 2016
The article presents data on the prevalence of chronic obstructive pulmonary disease and economic losses to which it leads. The emphasis is placed on the relevance of developing adequate rehabilitation measures for patients. A special place is devoted to
N. I. Maistruk
doaj   +3 more sources

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Modelling the longitudinal measurement of chronic obstructive pulmonary disease outpatient follow-up in the northwestern Ethiopia

open access: yesScientific Reports, 2023
Chronic obstructive pulmonary disease is a condition which can be prevented and treated and is characterized by difficulty of breathing that is not entirely curable.
Yoseph Kassa   +2 more
doaj   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson   +12 more
wiley   +1 more source

An Optoelectrically Switched, Dual‐Mode Neuromorphic Sensor for Transient and Accumulative Gas Detection

open access: yesAdvanced Functional Materials, EarlyView.
A transistor‐type carbon nanotube gas sensor with dual‐mode detection capability has been proposed. By simply adjusting the gate voltage and UV illumination, this sensor enables both real‐time detection and accumulation‐based sensing of toxic gases within a single device, providing a compact and adaptable platform for environmental monitoring ...
Jaewon Shin   +7 more
wiley   +1 more source

Transcriptional Dynamics of NRF2 Overexpression and KEAP1-NRF2 Inhibitors in Human Cell Line and Primary Lung Cells

open access: yesAntioxidants
Oxidative stress in the human lung is caused by both internal (e.g., inflammation) and external stressors (smoking, pollution, and infection) to drive pathology in a number of lung diseases.
Corinne Hamblet   +10 more
doaj   +1 more source

Adoption and adherence to chronic obstructive pulmonary disease GOLD guidelines in a primary care setting

open access: yesSAGE Open Medicine, 2019
Objectives: Over 380 million people in the world live with chronic obstructive pulmonary disease, and it is the third leading cause of death in the United States. Despite updated guidelines, there may be significant variations in diagnosis and management
Salim Surani   +8 more
doaj   +1 more source

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