Results 121 to 130 of about 1,412,546 (392)

Imaging of acute pulmonary embolism: an update.

Cardiovascular Diagnosis and Therapy, 2018
Imaging plays an important role in the evaluation and management of acute pulmonary embolism (PE). Computed tomography (CT) pulmonary angiography (CTPA) is the current standard of care and provides accurate diagnosis with rapid turnaround time.
Alastair Moore, J. Wachsmann, M. Chamarthy, Lloyd Panjikaran, Y. Tanabe, P. Rajiah   +5 more
semanticscholar   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Intermediate-high risk pulmonary embolism: When teamwork really matters

Thrombosis Update
Pulmonary embolism is a common disease associated with significant morbidity and mortality. Existing validated risk stratification tools have enabled the rapid identification of patients with low versus high-risk pulmonary embolism.
Bibi Ayesha Bassa, Elizabeth Little, Izak Loftus, Leah Flanagan, Andrew Neil, Tomás Breslin, Cian McDermott   +6 more
doaj   +1 more source

Critical Care Ultrasonography and Its Application for COVID-19 [PDF]

, 2020
Ultrasound has developed as an invaluable tool in diagnosis and proper management in the intensive care unit (ICU). Application of critical care ultrasonography is quite distinct from the routine comprehensive diagnostic ultrasound exam, because the ...
Chong, MD, Weelic, Hai, MD, Yang, Liu, MD, Ji-Bin, Liu, MD, Xi, Ma, MD, Bin   +4 more
core   +1 more source

Cancer patients’ experiences of living with venous thromboembolism: A systematic review and qualitative thematic synthesis [PDF]

, 2018
Background: Cancer-Associated thrombosis is common. Recommended treatment is daily injected low-molecular-weight heparin for 6months. Most studies focus on prophylaxis and treatment; few have explored patients’ experience.
Benelhaj, Naima B., Hutchinson, Ann, Ilyas, Muhammad Waqas, Johnson, Miriam J., Maraveyas, Anthony M., Seymour, Julie D.   +5 more
core   +1 more source

Hospital volume and outcomes for acute pulmonary embolism: multinational population based cohort study

British medical journal, 2019
Objectives To evaluate the association between experience in the management of acute pulmonary embolism, reflected by hospital case volume, and mortality. Design Multinational population based cohort study using data from the Registro Informatizado de la
D. Jiménez, B. Bikdeli, A. Quezada, A. Muriel, J. Lobo, J. de Miguel-Díez, L. Jara-Palomares, P. Ruiz-Artacho, R. Yusen, M. Monreal   +9 more
semanticscholar   +1 more source

CRISPR‐Cas9‐Loaded Theranostic Liposomes for Enhancing Radiosensitization of Prostate Cancer through POLD4 Gene Editing under Real‐Time MRI Monitoring

Advanced Science, EarlyView.
This study identifies POLD4 as a potential prostate cancer radiosensitization target through transcriptome sequencing. By encapsulating POLD4‐targeted CRISPR/Cas9 plasmids and USPIONs in cationic liposomes, an MRI‐monitored gene‐editing platform is established.
Xuhui Fan, Ruru Zhang, Linjun Yang, Shixiong Chen, Meijuan He, Yongqiang Wang, Linjie Huang, Jianfeng Zeng, Shuwang Wu, Mingyuan Gao, Han Wang   +10 more
wiley   +1 more source

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

Advanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou, Yingying Zhang, Peng Zhou, Haofang Wan, Lingling Li, Bin Xu, Yuping Wan, Yingming Song, Yi Kang, Hongbo Zhang, Min Shi, Qun Hou, Jiehong Yang, Chen Ding, Wei Fu, Buchang Zhao, Haitong Wan   +16 more
wiley   +1 more source

Diagnosis and Thrombolytic Management of Massive Intraoperative Pulmonary Embolism Guided by Point of Care Transthoracic Echocardiography

Case Reports in Anesthesiology, 2018
Perioperative pulmonary embolism can go undetected until the sudden onset of cardiopulmonary collapse. Point of care echocardiography in such setting can narrow the differential diagnosis of precipitous instability and facilitate tailored, rather than ...
Roman Dudaryk, Julio Benitez Lopez, Jack Louro   +2 more
doaj   +1 more source

Fibrinolysis for patients with intermediate-risk pulmonary embolism.

New England Journal of Medicine, 2014
BACKGROUND The role of fibrinolytic therapy in patients with intermediate-risk pulmonary embolism is controversial. METHODS In a randomized, double-blind trial, we compared tenecteplase plus heparin with placebo plus heparin in normotensive patients ...
G. Meyer, E. Vicaut, T. Danays, G. Agnelli, C. Becattini, J. Beyer-Westendorf, E. Bluhmki, H. Bouvaist, B. Brenner, F. Couturaud, C. Dellas, K. Empen, A. França, N. Galiè, A. Geibel, S. Goldhaber, D. Jiménez, M. Kozak, C. Kupatt, N. Kucher, I. Lang, M. Lankeit, N. Meneveau, G. Pacouret, M. Palazzini, A. Petriş, P. Pruszczyk, M. Rugolotto, A. Salvi, S. Schellong, M. Sebbane, B. Sobkowicz, B. Stefanović, H. Thiele, A. Torbicki, F. Verschuren, S. Konstantinides   +36 more
semanticscholar   +1 more source