Results 81 to 90 of about 4,815,425 (278)

Pulmonary embolism severity index accurately predicts long-term mortality rate in patients hospitalized for acute pulmonary embolism [PDF]

European Heart Journal, 2013
The Pulmonary Embolism (PE) Severity Index (PESI) is a clinical prognostic rule that accurately classifies PE patients into five risk classes with increasing mortality. PESI score has been validated in studies with a relatively short-term follow-up and its accuracy in predicting long-term prognosis has never been established.Consecutive patients ...
DENTALI, FRANCESCO, Riva, N., Turato, S., Grazioli, S., SQUIZZATO, ALESSANDRO, Steidl, L., GUASTI, LUIGINA, GRANDI, ANNA MARIA, AGENO, WALTER   +8 more
openaire   +2 more sources

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Association between severity of pulmonary embolism and health-related quality of life. [PDF]

Background: Health-related quality of life (QoL) impairment is common after pulmo- nary embolism (PE). Whether the severity of the initial PE has an impact on QoL is unknown.
Aujesky, Drahomir, Magyar, Ursula, Rodondi, Nicolas, Méan, Marie, Tritschler, Tobias, Righini, Marc Philip, Stalder, Odile, Righini, Marc, Schuetz, Philipp, Bassetti, Stefano, Baumgartner, Christine   +10 more
core   +2 more sources

Interleukin-6 and airflow limitation in chemical warfare patients with chronic obstructive pulmonary disease [PDF]

Objectives: Chronic obstructive pulmonary disease (COPD) is one of the main late complications of sulfur mustard poisoning. The aim of this study was to evaluate serum levels of interleukin (IL)-6 in war veterans with pulmonary complications of sulfur ...
خواجه دلوئی, محمد, Shahrzad Lari, توحیدی, محمد, آیت اللهی, حسین, محمدزاده لاری, شهرزاد, قبادی مراللو, حسن, عطاران, داود, بصیری, رضا, قانعی, مصطفی   +8 more
core   +1 more source

A Large Retrospective Study to Evaluate Utility of Zephyr Covered Stent in Transcatheter Closure of Sinus Venosus Defects

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter closure (TCC) of sinus venosus defects (SVD) using balloon‐expandable covered stents is an emerging alternative to surgery. ZephyrCS (Sahajanand Laser Technologies, Gandhinagar, India) is available in long lengths to suit SVD closure.
Pramod Sagar, Puthiyedath Thejaswi, Kothandam Sivakumar, Praveen Ashok Kumar   +3 more
wiley   +1 more source

Prognostic value of computed tomography pulmonary angiography in patients with acute pulmonary embolism

Egyptian Journal of Chest Disease and Tuberculosis
Background Pulmonary embolism (PE) is a serious illness. Identifying prognostic factors for PE may help in the management of those patients. Aim This study’s objective was to evaluate the prognostic value of computed tomography pulmonary artery ...
Amany O. M. Omar, Yousef A. Y. Ahmed, Abd-E. A. A. Elfadl, A. H. Ali, Amal A. Abdelrahman, Khaled M. A. Shehata   +5 more
doaj   +1 more source

Reporte de caso: tromboembolia pulmonar aguda y trombo interauricular en foramen oval permeable

Cirugía Cardiovascular
Resumen: En el tromboembolismo pulmonar (TEP) agudo existen algunas condiciones que pueden cambiar la indicación de un manejo médico a uno quirúrgico, como por ejemplo la presencia de trombos intracavitarios asociado a un índice de severidad en el ...
Ubaldo Ernesto Rivas-Aguilar, Andrés Ramírez Vélez, Yamile Muñoz Perez, Sharoon de Jesús Suarez-Ramírez, Eric Edward Vinck-Geerman, Bruno Ramírez Castillero   +5 more
doaj   +1 more source

The assessment of acute pulmonary embolism severity using CT angiography features

International Journal of Emergency Medicine, 2020
Background This study was conducted to detect the association between radiologic features of CT pulmonary angiography (CTPA) and pulmonary embolism severity index (PESI).
Azin Shayganfar, Somayeh Hajiahmadi, Mohsen Astaraki, Shadi Ebrahimian   +3 more
doaj   +1 more source

Enhancing Evidence Generation by Linking Randomized Clinical Trials to Real‐World Data: The INVESTED‐Medicare Linkage Study

Clinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho, HoJin Shin, Mehdi Najafzadeh, Brian Claggett, Janinne Ortega‐Montiel, Jun Liu, Julie M. Paik, Narlina F. Lalani, Marie C. Bradley, John Concato, Scott D. Solomon, Orly Vardeny, Elisabetta Patorno   +12 more
wiley   +1 more source