Results 71 to 80 of about 8,089 (207)

Sympatho‐Excitation in Pulmonary Hypertension: The Potential Role of Pulmonary Arterial Baroreceptors: An Acute Physiologic Intervention Study

Respirology, Volume 31, Issue 6, Page 621-629, June 2026.
Pulmonary arterial baroreceptors reflexively stimulate sympathetic nerve activity (SNA) in response to elevated pulmonary artery pressure and distension. In pulmonary hypertension patients, changes in muscle SNA were proportional to changes in pulmonary haemodynamics following nebulised iloprost.
Michael J. Plunkett, Ana L. C. Sayegh, Robert A. Lewis, Tanya J. McWilliams, Sasiharan Sithamparanathan, Julian F. R. Paton, James P. Fisher   +6 more
wiley   +1 more source

Magnetic resonance imaging of pulmonary arterial compliance after pulmonary endarterectomy

, 2020
Pulmonary endarterectomy (PEA) is the treatment of choice of chronic thromboembolic pulmonary hypertension (CTEPH) [1]. However, successfully operated patients may continue to suffer from dyspnoea and limitation of exercise capacity, despite improvement ...
Gabriele Crimi, Stefano Ghio, Valentini, Adele, Luigi Oltrona Visconti, Celentano, Anna, D'Armini, Andrea Maria Aria A.M., Adele Valentini, Anna Celentano, Crimi, Gabriele, Pin, Maurizio, Scelsi, Laura, Turco, Annalisa, Visconti, Luigi Oltrona, Ghio, S., Maurizio Pin, Raineri, Claudia, Laura Scelsi, Annalisa Turco, Guida, Stefania, Stefania Guida, Andrea Maria D'Armini, Claudia Raineri, Robert Naeije, Naeije, Robert   +23 more
core   +1 more source

Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review of the Most Updated Literature [PDF]

, 2022
Pulmonary endarterectomy (PEA) is the treatment of choice in case of chronic thromboembolic pulmonary hypertension (CTEPH). PEA is performed by an increasing number of surgeons; however, the reported outcomes are limited to a few registries or to ...
Eleonora Faccioli, Faccioli, Eleonora, Andrea Dell’Amore, Boscolo, Annalisa, Navalesi, Paolo, Dell’Amore, Andrea, Martina Perazzolo Marra, Perazzolo Marra, Martina, Rea, Federico, Vincenzo Verzeletti, Paolo Navalesi, Schiavon, Marco, Annalisa Boscolo, Federico Rea, Marco Schiavon, Verzeletti, Vincenzo   +15 more
core   +1 more source

Ligand‐Independent Activation of Notch1 by Cathepsin L Induces CUX1/p16INK4a‐Dependent Endothelial Senescence Associated With Atherosclerosis

Aging Cell, Volume 25, Issue 6, June 2026.
CTSL activates Notch1/RBPJ in a ligand‐independent fashion, inducing CUX1/p16INK4a‐dependent endothelial senescence associated with atherosclerosis. ABSTRACT Our post‐GWAS functional analysis revealed that cathepsin L (CTSL) is an upstream regulator of CUX1, and it induces p16INK4a‐dependent and atherosclerosis‐associated senescence by indirectly ...
Yuwei Wu, Lili Lu, Shaoyang Yan, Zewen Du, Danli Jiang, Ting Wu, Qichao Wu, Jie Liu, Johny Ebin, Wei Sun, Partha Dutta, Jay Xiaojun Tan, Jonathan K. Alder, Gang Li   +13 more
wiley   +1 more source

Perioperative management of massive pulmonary hemorrhage after pulmonary endarterectomy

, 2018
Background: This study aims to evaluate our approaches and outcomes in patients who developed hemoptysis following pulmonary endarterectomy. Methods: Pulmonary endarterectomy was performed in 460 patients at Kartal Kosuyolu Training and Research Hospital
YILDIZELİ, BEDRETTİN, OLGUN YILDIZELİ, ŞEHNAZ   +1 more
core   +1 more source

Chronic thromboembolic pulmonary hypertension – surgical treatment options and our experience

Zdravniški Vestnik, 2009
Background: Chronic thromboembolic pulmonary hypertension is an increasingly recognized cause of pulmonary hypertension. Th e prognosis of untreated patients is poor.
Matevž Herlander, Barbara Salobir, Matjaž Turel, Boris Devčič, Marjeta Terčelj   +4 more
doaj  

Sugammadex Vs. Neostigmine for Cerebral Perfusion During Emergence From General Anesthesia in Patients Undergoing Carotid Endarterectomy: A Double‐Blind Randomized Controlled Trial

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
In this double‐blind RCT involving 82 patients undergoing carotid endarterectomy, sugammadex significantly reduced excessive cerebral blood flow during emergence from general anesthesia compared to neostigmine (MCAV% S: 24,600 vs. 31,575, p = 0.044). Sugammadex also shortened extubation time (110 vs.
Xuefei Jia, Wenbo Cao, Tianying Li, Qinghai Liu, Yi An, Lixia Li, Zhongjia Li, Chuanyu Liang, Pei Wang, Hongyi Song, Ke Cui, Manke Luo, Shuning Zhang, Xiaoxu Chen, Zhiwei Wu, Boyuan Li, Tianlong Wang, Liqun Jiao, Xiaoyang Li, Lei Zhao   +19 more
wiley   +1 more source

Anesthetic management of chronic thromboembolic pulmonary hypertension for surgical pulmonary thromboendarterectomy: A narrative review

Journal of Anaesthesiology Clinical Pharmacology
Chronic thromboembolic pulmonary hypertension (CTEPH) is caused due to the total or partial occlusion of the pulmonary vasculature due to organized thrombus, leading to severe pulmonary hypertension and eventually right heart failure, which makes ...
Sambhunath Das, KG Krithika
doaj   +1 more source

Aseptic meningitis due to intravenous immunoglobulin therapy (IVIG) in therapy‐refractory pyoderma gangraenosum

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina A. Kälber, Knut Schäkel, Alexander Enk, Julia K. Winkler   +3 more
wiley   +1 more source

Complementary multi‐omics profiling of chronic thromboembolic pulmonary hypertension reveals immune cell alterations, epigenetic changes, and genetically supported candidate genes

Animal Models and Experimental Medicine, Volume 9, Issue 4, Page 641-651, April 2026.
This study presents an integrative multi‐omics framework to uncover the molecular mechanisms and potential biomarkers of chronic thromboembolic pulmonary hypertension (CTEPH). Anthropometric and biochemical data were correlated using canonical correlation analysis, revealing key cardiometabolic associations. Single‐cell RNA sequencing identified immune
Xiaopeng Liu, Xia Zheng, Yajun Zhang, Yinghui Fang, Yanan Zhen   +4 more
wiley   +1 more source