Results 91 to 100 of about 1,690,762 (327)

A comparative study of bronchodilator response: utilizing pre-bronchodilator versus predicted normal values

open access: yesBMC Pulmonary Medicine
Background A positive bronchodilator response has been defined as a 12% increase in the forced expiratory volume in one second (FEV1) or forced vital capacity (FVC) from their respective pre-bronchodilator values, combined with at least a 0.2 L absolute ...
Afe Alexis   +3 more
doaj   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer   +10 more
wiley   +1 more source

Impaired pulmonary function after treatment for tuberculosis: the end of the disease?

open access: yesJornal Brasileiro de Pneumologia
Objective: To evaluate the prevalence of pulmonary function abnormalities and to investigate the factors affecting lung function in patients treated for pulmonary tuberculosis.
Mikhail Ivanovich Chushkin   +1 more
doaj   +1 more source

Structured Light Plethysmography (SLP): Management and follow up of a paediatric patient with pneumonia

open access: yesRespiratory Medicine Case Reports, 2017
Structured Light Plethysmography (SLP) is a non-invasive method to study chest and abdominal movement during breathing and can identify abnormal contributions of the different regions of the chest.
Michele Ghezzi   +4 more
doaj   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson   +12 more
wiley   +1 more source

An Optoelectrically Switched, Dual‐Mode Neuromorphic Sensor for Transient and Accumulative Gas Detection

open access: yesAdvanced Functional Materials, EarlyView.
A transistor‐type carbon nanotube gas sensor with dual‐mode detection capability has been proposed. By simply adjusting the gate voltage and UV illumination, this sensor enables both real‐time detection and accumulation‐based sensing of toxic gases within a single device, providing a compact and adaptable platform for environmental monitoring ...
Jaewon Shin   +7 more
wiley   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao   +8 more
wiley   +1 more source

Normalization of Lung Function following Treatment of Secondary Usual Interstitial Pneumonia: A Case Report

open access: yesClinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2015
Usual interstitial pneumonia (UIP) is the most common idiopathic interstitial pneumonia (IIP) and is associated with a poor prognosis and poor responsiveness to immunosuppressive therapy. We present a case of a woman with steroid-responsive biopsy-proven
Laurie A. Hohberger   +3 more
doaj   +1 more source

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