Results 131 to 140 of about 402,036 (336)

The Route to Artery Mimetics: Hybrid Bioinks for Embedded Bioprinting of Multimaterial Cylindrical Models

open access: yesAdvanced Functional Materials, EarlyView.
The fabrication of a cellularized, multilayered 3D printed cylindrical model comprising hybrid bioinks inspired by the natural extracellular environment as an approach to artery mimetics, is presented. Using embedded bioprinting, interlayer crosslinking of self‐supporting concentric cylinders is achieved.
Uxue Aizarna‐Lopetegui   +7 more
wiley   +1 more source

Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi   +6 more
wiley   +1 more source

Normalization of Lung Function following Treatment of Secondary Usual Interstitial Pneumonia: A Case Report

open access: yesClinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2015
Usual interstitial pneumonia (UIP) is the most common idiopathic interstitial pneumonia (IIP) and is associated with a poor prognosis and poor responsiveness to immunosuppressive therapy. We present a case of a woman with steroid-responsive biopsy-proven
Laurie A. Hohberger   +3 more
doaj   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer   +10 more
wiley   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson   +12 more
wiley   +1 more source

Low income as a determinant of exercise capacity in COPD. [PDF]

open access: yes, 2019
Exercise capacity (EC) is a critical outcome in chronic obstructive lung disease (chronic obstructive pulmonary disease (COPD)). It measures the impact of the disease and the effect of specific interventions like pulmonary rehabilitation (PR).
Benzo, Roberto   +4 more
core  

Infant Pulmonary Function Testing in Pediatric Diffuse Parenchymal Lung Disease

open access: yesCHEST Pulmonary
Topic Importance: Diffuse parenchymal lung disease (DPLD) in pediatrics, also known as children’s interstitial lung disease, comprises a diverse group of rare and chronic respiratory disorders affecting the pediatric population. Diagnosing and monitoring
Avigdor Hevroni, MD   +8 more
doaj   +1 more source

An Optoelectrically Switched, Dual‐Mode Neuromorphic Sensor for Transient and Accumulative Gas Detection

open access: yesAdvanced Functional Materials, EarlyView.
A transistor‐type carbon nanotube gas sensor with dual‐mode detection capability has been proposed. By simply adjusting the gate voltage and UV illumination, this sensor enables both real‐time detection and accumulation‐based sensing of toxic gases within a single device, providing a compact and adaptable platform for environmental monitoring ...
Jaewon Shin   +7 more
wiley   +1 more source

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