Results 211 to 220 of about 1,035,671 (315)

Airborne Particulate Concentrations During and After Pulmonary Function Testing. [PDF]

open access: yesChest, 2021
Li J   +8 more
europepmc   +1 more source

Machine Learning‐Enabled Drug‐Induced Toxicity Prediction

open access: yesAdvanced Science, EarlyView.
Unexpected toxicity accounts for 30% of drug development failures. This review highlights ML innovations in predicting drug‐induced toxicity, emphasizing comparative analyses, interpretable algorithms, and multi‐source data integration. It categorizes toxicity types, summarizes ML models, and organizes key databases, offering strategies to address ...
Changsen Bai   +5 more
wiley   +1 more source

The prognostic value of clinical frailty scale and outcomes in older patients undergoing left ventricular assist device implantation

open access: yesAGING MEDICINE, Volume 5, Issue 4, Page 257-263, December 2022., 2022
The main finding in our study is that Clinical Frailty Scale‐defined frailty status was predictive of 1‐year post‐interventional mortality after left ventricular assist device implantation. Abstract Objectives Heart failure impacts patients’ functional capabilities, ultimately leading to frailty.
Temitope Ajibawo   +3 more
wiley   +1 more source

Pulmonary function testing in pediatric allogeneic stem cell transplant recipients to monitor for Bronchiolitis obliterans syndrome: a systematic review. [PDF]

open access: yesBMC Pediatr
Gower WA   +15 more
europepmc   +1 more source

ADAR1‐HNRNPL‐Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease

open access: yesAdvanced Science, EarlyView.
ADAR1‐HNRNPL interaction‐repressed circCANX recruits P53 mRNA and UPF1 to assemble a complex in nuclear. This complex promotes P53 mRNA degradation through the NMD pathway, and finally reduces autophagy and stress granules formation to further regulate inflammation.
Ting‐Ting Chen   +10 more
wiley   +1 more source

Prevalence of chronic respiratory diseases diagnosed by pulmonary function testing: a cross-sectional study. [PDF]

open access: yesAnn Med Surg (Lond)
Alnoor SAM   +6 more
europepmc   +1 more source

SENP3 Drives Abdominal Aortic Aneurysm Development by Regulating Ferroptosis via De‐SUMOylation of CTH

open access: yesAdvanced Science, EarlyView.
In this study, it is proposed that SENP3 accumulates in macrophages of aneurysmal aortic tissues, which promotes macrophage ferroptosis and inflammation via regulation of CTH de‐SUMOylation. Abstract Abdominal aortic aneurysm (AAA) is a high‐risk inflammatory disorder. SENP3, a SUMO2/3‐specific protease, is closely involved in the development of cancer.
Long Chen   +15 more
wiley   +1 more source

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