Results 261 to 270 of about 428,889 (351)
CIDEC Restricts Liver Regeneration by Disturbing Lipid Droplet Triglyceride Turnover
This study identifies CIDEC, an lipid droplet (LD)‐fusion associated protein upregulated by CREBH during early regeneration, as a negative regulator of liver regeneration through its unexpected role in sequestering triglyceride (TG) within LDs. CIDEC depletion reduces LD size, mobilizes LD‐stored TG, enhances TG catabolism and free fatty acid (FFA ...
Feng Ouyang +16 more
wiley +1 more source
Chest CT imaging for differentiating normal, PRISm, and COPD in comparison with pulmonary function tests [PDF]
Zongjing Ma +7 more
openalex +1 more source
The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan +9 more
wiley +1 more source
Chloral hydrate sedation for infant pulmonary function testing
Clement L. Ren +2 more
openalex +2 more sources
The role of germline WWOX loss‐of‐function variants in oncogenesis has remained poorly characterized. This study provides the first comprehensive genetic and functional evidence that such variants promote tumorigenesis through the disruption of multiple tumor‐suppressive mechanisms.
Xiaopeng Zhang +8 more
wiley +1 more source
"EFFECT OF TYPE 2 DIABETES MELLITUS ON DYNAMIC PULMONARY FUNCTION TESTS"
BLDE University
openalex +1 more source
Targeted Expansion of Treg Cells to Induce Immune Tolerance after Kidney Transplantation
A dual‐targeting nanoparticle platform that selectively engages graft stromal cells via CD248 receptors while employing kidney‐ specific promoters (NPHS2) to drive localized IL‐ 2/TGF‐βexpression is developed. This approach achieves three therapeutic objectives:1) intragraft Treg polarization without systemic cytokine exposure;2) reduced dependence on ...
Tong Lu +18 more
wiley +1 more source

