Results 41 to 50 of about 235,302 (301)

Using Operational Analysis to Improve Access to Pulmonary Function Testing

Canadian Respiratory Journal, 2016
Background. Timely pulmonary function testing is crucial to improving diagnosis and treatment of pulmonary diseases. Perceptions of poor access at an academic pulmonary function laboratory prompted analysis of system demand and capacity to identify ...
Ada Ip, Raymond Asamoah-Barnieh, Diane P. Bischak, Warren J. Davidson, W. Ward Flemons, Sachin R. Pendharkar   +5 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Use of Pulmonary Function Testing for Patients with a Diagnosis of Asthma in a Large Urban and Suburban Health System in the United States [PDF]

, 2021
M. Restko, C. Chen, Polina Imas, Shawn D. Aaron, Shashi Bellam   +4 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Age, gender, and pulmonary diseases in compliance with pulmonary function testing

Medicine Science
Pulmonary function tests (PFTs) are critical tools for the diagnosis and monitoring of respiratory diseases. However, patient compliance with the test affects the reliability of the results. This study was designed to analyze factors such as age, gender,
Maside Ari, Berna Akinci Ozyurek, Omer Faruk Tuten, Esma Dolmus, Tunahan Dolmus   +4 more
doaj   +1 more source

Swimming-induced changes in pulmonary function: special observations for clinical testing

BMC Sports Science, Medicine and Rehabilitation, 2021
Background A special improvement in pulmonary function is found in swimmers. In clinical testing the airway reactivity is observed at certain exercise intensity and target ventilation. However, in highly trained swimmers exercising in water the reactions
Marja Päivinen, Kari Keskinen, Heikki Tikkanen   +2 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Diagnostic value of post-bronchodilator pulmonary function testing to distinguish between stable, moderate to severe COPD and asthma

International Journal of COPD, 2008
Daphne C Richter1, James R Joubert1, Haylene Nell1, Mace M Schuurmans2, Elvis M Irusen21Tiervlei Trial Centre, Karl Bremer Hospital, Bellville, RSA; 2Respiratory Research Unit, Department of Internal Medicine, Faculty of Health Sciences, University of ...
Daphne C Richter, James R Joubert, Haylene Nell, Mace M Schuurmans, Elvis M Irusen   +4 more
doaj  

Assessment of fitness and exercise tolerance of chronic obstructive pulmonary disease patients in correlation with their lifestyle

The Egyptian Journal of Bronchology, 2016
Background Chronic obstructive pulmonary disease (COPD) is a progressive, chronic disease in which the patient’s nutritional status is critical for optimizing outcomes. Pulmonary system abnormalities certainly limit exercise in patients with COPD. Aim of
Mohammad A. E. Faramawy, Emad E. A. Korraa, Ibrahim A. Dwedar, Nermine M. Riad, Mohammed A. M. Nada   +4 more
doaj   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source